Evidence map›Paper›PMID 30848025›Full record

Trial reportThe Kaohsiung journal of medical sciences2019

The use of remifentanil in critically ill patients undergoing percutaneous dilatational tracheostomy: A prospective randomized-controlled trial.

Si-Yuan Chang, Rong-Qing Sun, Min Feng, Gang Liu, Da-Qian Xu, Hai-Li Wang, Yu-Ming Xu

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in The Kaohsiung journal of medical sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Si-Yuan ChangDepartment of Stroke Intensive Care Unit, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Rong-Qing SunDepartment of Stroke Intensive Care Unit, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Min FengDepartment of Stroke Intensive Care Unit, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Gang LiuDepartment of Stroke Intensive Care Unit, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Da-Qian XuDepartment of Stroke Intensive Care Unit, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Hai-Li WangDepartment of Stroke Intensive Care Unit, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Yu-Ming XuDepartment of Neurology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
First Affiliated Hospital of Zhengzhou University · CN

Funding

Hospital Science Fund for Young Scholars
6 · The paper itself

Abstract

Remifentanil was a μ-agonist, with a rapid onset, a powerful narcotic analgesic activity and a fast nonspecific esterases hydrolyzation and theoretically an ideal opioid for percutaneous dilatational tracheostomy (PDT). The present study discussed use of remifentanil in critically ill patients undergoing PDT. Ninety-nine patients were randomly assigned to the propofol/remifentanil group (PR group, n = 49) or the propofol group (P group, n = 50). Two patients (one in P group and one in PR group) were excluded and transferred to surgical way of tracheostomy because of uncontrolled bleeding. The primary outcomes were critical care pain observation (CPOT) scores during PDT; hemodynamic response and side effects, such as bleeding and muscle rigidity (MR). CPOT scores in P group were significantly higher than in PR group during incision and dilation stages (P < 0.05 and P < 0.01). Systolic blood pressure had a significant drop after a bolus of remifentanil in PR group compared with patients in P group (P < 0.056). The incidence of MR was significantly higher in PR group than in P group (P < 0.05). Recovery time in PR group was significantly shorter than in P group (P < 0.05). The occurrence of tachycardia, bleeding, vomiting, and nausea had no statistically differences in both groups. Patients in PR group were undergoing shorter recovery time and better experience of pain in PDT compared with patients in P group, but MR seemed to be higher in PR group. Remifentanil seemed to be a safe and effective opioid used in critically ill patients undergoing PDT.

Indexed as

Critical IllnessTracheostomyAdultFemaleHemodynamicsHumansMalePainPropofolProspective StudiesRemifentanilVisual Analog ScalePropofolRemifentanilintensive care unitopioidspercutaneous dilatational tracheostomypropofolremifentanil

Identifiers

PMID30848025
PMCPMC11900691
OpenAlexW2921094391

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.