Evidence map›Paper›PMID 30847623›Full record

ArticleEuropean archives of psychiatry and clinical neuroscience2021

Cortical thickness 20 years after diagnosis of anorexia nervosa during adolescence.

Josefina Castro-Fornieles, Elena de la Serna, Anna Calvo, José Pariente, Susana Andrés-Perpiña, Maria Teresa Plana, Sonia Romero, Itziar Flamarique, Miguel Gárriz, Núria Bargalló

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In one paragraph

Article in European archives of psychiatry and clinical neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Neuroimaging and eating disorders.Current opinion in psychiatry · 2019
    Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Josefina Castro-FornielesChild and Adolescent Psychiatry and Psychology Department, 2017SGR881, Institute Clínic of Neurosciences, Hospital Clínic of Barcelona, CIBERSAM, IDIBAPS, Villarroel 170, Barcelona, 08036, Spain. jcastro@clinic.ub.es.ORCID http://orcid.org/0000-0003-0632-2687
Elena de la SernaChild and Adolescent Psychiatry and Psychology Department, 2017SGR881, Institute Clínic of Neurosciences, Hospital Clínic of Barcelona, CIBERSAM, IDIBAPS, Villarroel 170, Barcelona, 08036, Spain.
Anna CalvoMagnetic Resonance Image Core Facility, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.
José ParienteMagnetic Resonance Image Core Facility, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.
Susana Andrés-PerpiñaChild and Adolescent Psychiatry and Psychology Department, 2017SGR881, Institute Clínic of Neurosciences, Hospital Clínic of Barcelona, CIBERSAM, IDIBAPS, Villarroel 170, Barcelona, 08036, Spain.
Maria Teresa PlanaChild and Adolescent Psychiatry and Psychology Department, 2017SGR881, Institute Clínic of Neurosciences, Hospital Clínic of Barcelona, CIBERSAM, IDIBAPS, Villarroel 170, Barcelona, 08036, Spain.
Sonia RomeroChild and Adolescent Psychiatry and Psychology Department, 2017SGR881, Institute Clínic of Neurosciences, Hospital Clínic of Barcelona, CIBERSAM, IDIBAPS, Villarroel 170, Barcelona, 08036, Spain.
Itziar FlamariqueChild and Adolescent Psychiatry and Psychology Department, 2017SGR881, Institute Clínic of Neurosciences, Hospital Clínic of Barcelona, CIBERSAM, IDIBAPS, Villarroel 170, Barcelona, 08036, Spain.
Miguel GárrizInstitute of Neuropsychiatry and Addictions (INAD), Parc de Salut MAR, Barcelona, Spain.
Núria BargallóMagnetic Resonance Image Core Facility, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.

Funding

Women's Institute, Ministry of Equality of Spain 234/09
6 · The paper itself

Abstract

objectiveThe objective of the present study is to evaluate cortical thickness (CT) abnormalities using FreeSurfer in adult subjects who had an onset of anorexia nervosa during their adolescence some 20 years previously, and to compare them with control subjects.

methodsFifty-four participants, including 26 women who were diagnosed and treated for AN during adolescence some 20 years previously and 28 healthy women of similar age and geographical area were assessed using structured interviews and MRI scans. Prior AN subjects were divided into two groups depending on their current eating disorder status (recovered or not recovered from any eating disorder). In all subjects, CT was measured using FreeSurfer.

resultsA significantly lower CT was observed in the eating disorder group than in the control group in the right post-central gyrus and the lateral occipital cortex. The recovered eating disorder group only had lower CT in the post-central gyrus. Within all subjects with prior AN, no correlations were found between lower CT in these areas and clinical variables. DISCUSSION: CT is reduced some 20 years after diagnosis of AN especially in the parietal and precentral areas, even in subjects without any current ED diagnosis.

Indexed as

Anorexia NervosaCerebral CortexAdultCase-Control StudiesFemaleFollow-Up StudiesHumansMagnetic Resonance ImagingMaleAnorexia nervosaCortical thicknessLong-term assessment

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.