Evidence map›Paper›PMID 30847576›Full record

ArticleMikrochimica acta2019

Low fouling electrochemical sensing in complex biological media by using the ionic liquid-doped conducting polymer PEDOT: application to voltammetric determination of dopamine.

Zhen Song, Ge Sheng, Yige Cui, Mengru Li, Zhiling Song, Caifeng Ding, Xiliang Luo

Abstract read
PubMed Publisher
In one paragraph

Article in Mikrochimica acta, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. In Situ Synthesis of a BiNanomaterials (Basel, Switzerland) · 2022
    Article
  5. Article
  6. Recent Advances in Ionic Liquids in Biomedicine.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021
    Review
  7. Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zhen SongKey Laboratory of Optic-electric Sensing and Analytical Chemistry for Life Science, MOE, Qingdao University of Science and Technology, Qingdao, 266042, People's Republic of China.
Ge ShengKey Laboratory of Optic-electric Sensing and Analytical Chemistry for Life Science, MOE, Qingdao University of Science and Technology, Qingdao, 266042, People's Republic of China.
Yige CuiKey Laboratory of Optic-electric Sensing and Analytical Chemistry for Life Science, MOE, Qingdao University of Science and Technology, Qingdao, 266042, People's Republic of China.
Mengru LiKey Laboratory of Optic-electric Sensing and Analytical Chemistry for Life Science, MOE, Qingdao University of Science and Technology, Qingdao, 266042, People's Republic of China.
Zhiling SongKey Laboratory of Optic-electric Sensing and Analytical Chemistry for Life Science, MOE, Qingdao University of Science and Technology, Qingdao, 266042, People's Republic of China.
Caifeng DingKey Laboratory of Optic-electric Sensing and Analytical Chemistry for Life Science, MOE, Qingdao University of Science and Technology, Qingdao, 266042, People's Republic of China.
Xiliang LuoKey Laboratory of Optic-electric Sensing and Analytical Chemistry for Life Science, MOE, Qingdao University of Science and Technology, Qingdao, 266042, People's Republic of China. xiliangluo@qust.edu.cn.ORCID http://orcid.org/0000-0001-6075-7089

Funding

National Natural Science Foundation of China 21675093, 21422504
6 · The paper itself

Abstract

An electrochemical sensor that can resist biofouling even when operated in complex biological medium is developed for the determination of dopamine. It is based on the use of the conducting polymer poly(3,4-ethylenedioxythiophene) (PEDOT) that is doped with the water insoluble ionic liquid (IL), 1-ethyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide. A glassy carbon electrode modified with PEDOT/IL is shown to enable accurate determination of dopamine, as a model analyte in the presence of high concentrations of proteins, and resist biological fouling even in native serum. It exhibited a low limit of detection of 33 nM for the detection of dopamine, with a wide linear range from 0.2 to 328 μM (at 0.2 V vs. saturated calomel electrode). The PEDOT/IL modified glassy carbon electrode has a porous microstructure, high electrical conductivity and good stability. The sensor can be used to quantify dopamine in human urine samples with satisfying accuracy. Graphical abstract An antifouling electrochemical sensor capable of detecting target in complex biological samples was developed based on the use of a conducting polymer (PEDOT) that was doped with a water insoluble ionic liquid.

Indexed as

AntifoulingConducting polymer nanocompositeDopamine determinationElectrochemical sensorsElectrodepositionPoly(3,4-ethylenedioxythiophene)

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.