ArticleAnnals of clinical and translational neurology2019
Slower alpha rhythm associates with poorer seizure control in epilepsy.
Article in Annals of clinical and translational neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 57 citations in OpenAlex.
- Assessing Strengths and Limitations of Magnetoencephalography Source Imaging With Intracerebral EEG.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Disease duration modulates BOLD representations of alpha oscillations in drug-resistant epilepsy: A concurrent EEG and fMRI study.Epilepsia · 2026Article
- Mapping Brain Lesions to Conduction Delays: The Next Step for Personalized Brain Models in Multiple Sclerosis.Human brain mapping · 2025Article
- Diagnosing Epilepsy with Normal Interictal EEG Using Dynamic Network Models.Annals of neurology · 2025Article
- A comprehensive investigation of intracortical and corticothalamic models of the alpha rhythm.PLoS computational biology · 2025Article
- Source Causal Connectivity Noninvasively Predicting Surgical Outcomes of Drug-Refractory Epilepsy.CNS neuroscience & therapeutics · 2025Article
- Article
- Alpha rhythm slowing in temporal lobe epilepsy across scalp EEG and MEG.Brain communications · 2024Article
- Impaired brain-heart axis in focal epilepsy: Alterations in information flow and implications for seizure dynamics.Network neuroscience (Cambridge, Mass.) · 2024Article
- Machine-learning for the prediction of one-year seizure recurrence based on routine electroencephalography.Scientific reports · 2023Article
- Global nonlinear approach for mapping parameters of neural mass models.PLoS computational biology · 2023Article
- Ambulatory Local Field Potential Recordings from the Thalamus in Epilepsy: A Feasibility Study.Stereotactic and functional neurosurgery · 2023Article
- Limited clinical validity of univariate resting-state EEG markers for classifying seizure disorders.Brain communications · 2023Article
- Electroencephalography characteristics related to risk of sudden unexpected death in epilepsy in patients with Dravet syndrome.Frontiers in neurology · 2023Article
- EEG Markers of Treatment Resistance in Idiopathic Generalized Epilepsy: From Standard EEG Findings to Advanced Signal Analysis.Biomedicines · 2022Review
- Seizure classification with selected frequency bands and EEG montages: a Natural Language Processing approach.Brain informatics · 2022Article
- Brivaracetam Modulates Short-Term Synaptic Activity and Low-Frequency Spontaneous Brain Activity by Delaying Synaptic Vesicle Recycling in Two Distinct Rodent Models of Epileptic Seizures.Journal of molecular neuroscience : MN · 2022Article
- Heterogeneity of resting-state EEG features in juvenile myoclonic epilepsy and controls.Brain communications · 2022Article
- Analysis of Clinical Characteristics, Background, and Paroxysmal Activity in EEG of Patients with Juvenile Myoclonic Epilepsy.Brain sciences · 2021Article
- A computational biomarker of juvenile myoclonic epilepsy from resting-state MEG.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2021Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
Objective: Slowing and frontal spread of the alpha rhythm have been reported in multiple epilepsy syndromes. We investigated whether these phenomena are associated with seizure control. Methods: We prospectively acquired resting-state electroencephalogram (EEG) in 63 patients with focal and idiopathic generalized epilepsy (FE and IGE) and 39 age- and gender-matched healthy subjects (HS). Patients were divided into good and poor (≥4 seizures/12 months) seizure control groups based on self-reports and clinical records. We computed spectral power from 20-sec EEG segments during eyes-closed wakefulness, free of interictal abnormalities, and quantified power in high- and low-alpha bands. Analysis of covariance and post hoc Results: Compared to HS, patients showed a statistically significant shift of spectral power from high- to low-alpha frequencies (effect size Interpretation: Alpha slowing and anteriorization are a robust finding in patients with epilepsy and might represent a generic indicator of seizure liability.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.