ArticleAnnals of clinical and translational neurology2019
A new counterintuitive training for adult amblyopia.
Article in Annals of clinical and translational neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
57 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Selective serotonin reuptake inhibitors for amblyopia treatment: a systematic review and meta-analysis of randomized controlled trials.Frontiers in neurologyPooled it
- Temporary retinal inactivation reverses effects of long-term monocular deprivation in visual cortex by induction of burst mode firing in the thalamus.Cell reports · 2025Article
- Breaking and restoring ocular balance: Temporal interactions in binocular rivalry and stereopsis.Journal of vision · 2025Article
- A Systematic Review and Meta-Analysis of Perceptual Learning and Video Game Training for Adults with Monocular Amblyopia.Ophthalmology and therapy · 2025Review
- The impact of eye movements on amblyopic vision: A mini-review.Vision research · 2025Review
- Contextual Binocular Imbalance Impairs Local Stereopsis.Investigative ophthalmology & visual science · 2025Article
- The interplay between Hebbian and homeostatic plasticity in the adult visual cortex.The Journal of physiology · 2025Article
- Physical exertion does not lead to a change in the time taken to correctly recognize stereoscopic stimuli in changing horizontal disparity levels.Frontiers in physiology · 2025Article
- Multisensory integration, brain plasticity and optogenetics in visual rehabilitation.Frontiers in neurology · 2025Review
- Ocular Dominance Plasticity: A Mini-Review.Eye and brain · 2025Review
- Evaluation of the clinical effect of 4D digital strabismus and amblyopia visual function correction system combined with traditional comprehensive treatment methods on anisometropic amblyopia.BMC ophthalmology · 2024Article
- Harnessing brain plasticity to improve binocular vision in amblyopia: An evidence-based update.European journal of ophthalmology · 2024Review
- Collective plasticity of binocular interactions in the adult visual system.Scientific reports · 2024Article
- Restoring vision in adult amblyopia by enhancing plasticity through deletion of the transcriptional repressor REST.iScience · 2024Article
- Acceleration of spontaneous visual recovery by voluntary physical exercise in adolescent amblyopic rats.Frontiers in cellular neuroscience · 2024Article
- Pretraining alpha rhythm enhancement by neurofeedback facilitates short-term perceptual learning and improves visual acuity by facilitated consolidation.Frontiers in neuroergonomics · 2024Article
- The Suppressive Basis of Ocular Dominance Changes Induced by Short-Term Monocular Deprivation in Normal and Amblyopic Adults.Investigative ophthalmology & visual science · 2023Article
- Integration and suppression interact in binocular vision.Journal of vision · 2023Article
- Measuring the reliability of binocular rivalry.Journal of vision · 2023Article
- Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: The aim of this study was to investigate whether short-term inverse occlusion, combined with moderate physical exercise, could promote the recovery of visual acuity and stereopsis in a group of adult anisometropic amblyopes. Methods: Ten adult anisometropic patients underwent six brief (2 h) training sessions over a period of 4 weeks. Each training session consisted in the occlusion of the amblyopic eye combined with physical exercise (intermittent cycling on a stationary bike). Visual acuity (measured with ETDRS charts), stereoacuity (measured with the TNO test), and sensory eye dominance (measured with binocular rivalry) were tested before and after each training session, as well as in follow-up visits performed 1 month, 3 months, and 1 year after the end of the training. Results: After six brief (2 h) training sessions, visual acuity improved in all 10 patients (0.15 ± 0.02 LogMar), and six of them also recovered stereopsis. The improvement was preserved for up to 1 year after training. A pilot experiment suggested that physical activity might play an important role for the recovery of visual acuity and stereopsis. Conclusions: Our results suggest a noninvasive training strategy for adult human amblyopia based on an inverse-occlusion procedure combined with physical exercise.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.