Evidence map›Paper›PMID 30847299›Full record

ArticleFrontiers in oncology2019

Association Between

Elisa Boldrin, Sandro Malacrida, Enrica Rumiato, Giorgio Battaglia, Alberto Ruol, Alberto Amadori, Daniela Saggioro

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Effect ofAmerican journal of translational research · 2020
    Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Elisa BoldrinImmunology and Molecular Oncology, Veneto Institute of Oncology IOV-IRCCS, Padova, Italy.
Sandro MalacridaEurac Research, Institute of Mountain Emergency Medicine, Bolzano, Italy.
Enrica RumiatoImmunology and Molecular Oncology, Veneto Institute of Oncology IOV-IRCCS, Padova, Italy.
Giorgio BattagliaEndoscopy Unit, Veneto Institute of Oncology IOV-IRCCS, Padova, Italy.
Alberto RuolDepartment of Surgical Sciences, Oncology and Gastroenterology, University of Padova, Padova, Italy.
Alberto AmadoriImmunology and Molecular Oncology, Veneto Institute of Oncology IOV-IRCCS, Padova, Italy.
Daniela SaggioroImmunology and Molecular Oncology, Veneto Institute of Oncology IOV-IRCCS, Padova, Italy.
Istituti di Ricovero e Cura a Carattere Scientifico · ITEurac Research · ITIstituto Oncologico Veneto · ITUniversity of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Esophageal cancer (EC) is a very aggressive tumor, and no reliable prognostic markers exist especially for resectable advanced neoplasia. The principal aim of this study was to investigate the association of germline polymorphisms in nucleotide excision repair (NER) pathway genes with the overall survival (OS) of patients with advanced EC. As a second aim, we also studied the association of NER gene variants with response to cisplatin-based chemotherapy. Among the EC patients referred to our Institution between 2004 and 2012, we selected a cohort of 180 patients diagnosed with a clinical tumor stage ranging from IIB and IVA. Patients were genotyped for four NER variants, two in the

Indexed as

ERCC1 C8092AERCC1 rs3212986ERCC2/XPD rs1799793esophageal cancergermline variantsoverall survivalXPD Asp312Asn

Identifiers

PMID30847299
PMCPMC6393335
OpenAlexW2915865761

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.