ReviewCardiac failure review2019
Heart Failure and Problems with Frailty Syndrome: Why it is Time to Care About Frailty Syndrome in Heart Failure.
Review in Cardiac failure review, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05888688 (The Imaging Assessment of Sarcopenia Across the Heart Failure Spectrum), which is not on this map. Cited by 30 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Imaging Assessment of Sarcopenia Across the Heart Failure Spectrum
Who cites it
30 citing papers in PubMed, 2 syntheses or guidelines pooled it, 54 citations in OpenAlex.
- Association between frailty and adverse outcomes after cardiac resynchronization therapy: a systematic review and meta-analysis.European geriatric medicine · 2025Pooled it
- Gender differences in the prevalence of frailty in heart failure: A systematic review and meta-analysis.International journal of cardiology · 2021Pooled it
- How do Japanese Patients with Chronic Heart Failure View Their Disease, Self-care, and Support?Advances in therapy · 2025Article
- State of the Art in Measuring Frailty in Patients With Heart Failure: from Diagnosis to Advanced Heart Failure.Current heart failure reports · 2025Review
- Frailty as Predictor for Early Functional Outcomes After Radical Prostatectomy.Journal of frailty, sarcopenia and falls · 2025Article
- Comparison of Physical Frailty Assessments in Heart Failure With Preserved Ejection Fraction.JACC. Advances · 2024Article
- RhoA/rho kinase pathway activation in age-associated endothelial cell dysfunction and thrombosis.Journal of cellular and molecular medicine · 2024Review
- Efficacy of empagliflozin in heart failure with preserved ejection fraction according to frailty status in EMPEROR-Preserved.Journal of cachexia, sarcopenia and muscle · 2024Article
- Weak grip strength predicts higher unplanned healthcare utilization among patients with heart failure.ESC heart failure · 2024Article
- Circulating H-FABP as a biomarker of frailty in patients with chronic heart failure.Experimental biology and medicine (Maywood, N.J.) · 2023Article
- The concurrent impact of mild cognitive impairment and frailty syndrome in heart failure.Archives of medical science : AMS · 2023Article
- Article
- Sex-based differences in referral of heart failure patients to outpatient clinics: a scoping review.ESC heart failure · 2022Article
- Employing the Multivariate Edmonton Scale in the Assessment of Frailty Syndrome in Heart Failure.Journal of clinical medicine · 2022Article
- The Impact of Frailty and Comorbidities on Heart Failure Outcomes.Cardiac failure review · 2022Review
- Association of frailty with in-hospital outcomes in elderly patients with heart failure.World journal of clinical cases · 2021Article
- A Simple Risk Score Based on Routine Clinical Parameters Can Predict Frailty in Hospitalized Heart Failure Patients.Journal of clinical medicine · 2021Article
- Frailty Among Asian Patients With Heart Failure.JACC. Asia · 2021Article
- Prevalence and Prognostic Significance of Frailty in Asian Patients With Heart Failure: Insights From ASIAN-HF.JACC. Asia · 2021Article
- Managing older patients with heart failure calls for a holistic approach.ESC heart failure · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Frailty syndrome (FS) is an independent predictor of mortality in cardiovascular disease and is found in 15-74% of patients with heart failure (HF). The syndrome has a complex, multidimensional aetiology and contributes to adverse outcomes. Proper FS diagnosis and treatment determine prognosis and support the evaluation of treatment outcomes. Routine FS assessment for HF patients should be included in daily clinical practice as an important prognostic factor within a holistic process of diagnosis and treatment. Multidisciplinary team members, particularly nurses, play an important role in FS assessment in hospital and primary care settings, and in the home care environment. Raising awareness of concurrent FS in patients with HF patients and promoting targeted interventions may contribute to a decreased risk of adverse events, and a better prognosis and quality of life.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.