Evidence map›Paper›PMID 30846984›Full record

ArticleFrontiers in immunology2019

Crucial Role of Nucleic Acid Sensing via Endosomal Toll-Like Receptors for the Defense of

Anna Hafner, Ulrike Kolbe, Isabel Freund, Virginia Castiglia, Pavel Kovarik, Tanja Poth, Franziska Herster, Markus A Weigand, Alexander N R Weber, Alexander H Dalpke and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
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  4. Interplay between group AMicrobiology and molecular biology reviews : MMBR · 2024
    Review
  5. Article
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  7. Article
  8. Review
  9. Inflammatory Response AgainstFrontiers in immunology · 2022
    Article
  10. Review
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 2 countries.

Anna HafnerDepartment of Infectious Diseases, Medical Microbiology and Hygiene, Heidelberg University Hospital, Heidelberg, Germany.
Ulrike KolbeDepartment of Infectious Diseases, Medical Microbiology and Hygiene, Heidelberg University Hospital, Heidelberg, Germany.
Isabel FreundDepartment of Infectious Diseases, Medical Microbiology and Hygiene, Heidelberg University Hospital, Heidelberg, Germany.
Virginia CastigliaMax F. Perutz Laboratories, University of Vienna, Vienna Biocenter, Vienna, Austria.
Pavel KovarikMax F. Perutz Laboratories, University of Vienna, Vienna Biocenter, Vienna, Austria.
Tanja PothCenter for Model System and Comparative Pathology, Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany.
Franziska HersterDepartment of Immunology, Interfaculty Institute of Cell Biology, Eberhard-Karls-University, Tübingen, Germany.
Markus A WeigandDepartment of Anesthesiology, Heidelberg University Hospital, Heidelberg, Germany.
Alexander N R WeberDepartment of Immunology, Interfaculty Institute of Cell Biology, Eberhard-Karls-University, Tübingen, Germany.
Alexander H DalpkeDepartment of Infectious Diseases, Medical Microbiology and Hygiene, Heidelberg University Hospital, Heidelberg, Germany.
Tatjana EigenbrodDepartment of Infectious Diseases, Medical Microbiology and Hygiene, Heidelberg University Hospital, Heidelberg, Germany.
University Hospital Heidelberg · DEHeidelberg University · DEUniversity of Tübingen · DEInstitute of Medical Microbiology and Hygiene · DEMax Perutz Labs · ATVienna Biocenter · AT

Funding

Austrian Science Fund FWF W 1261
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

BiomarkersCytokinesEndosomesHost-Pathogen InteractionsHumansImmunity, CellularImmunity, InnateNitric OxideNucleic AcidsReactive Oxygen SpeciesRNA, BacterialStreptococcal InfectionsStreptococcus pyogenesToll-Like ReceptorsBiomarkersCytokinesNitric OxideNucleic AcidsReactive Oxygen SpeciesRNA, BacterialToll-Like Receptorsbacterial RNAinnate immunitynucleic acidsskin infectionStreptococcus pyogenesTLR13UNC93B1

Identifiers

PMID30846984
PMCPMC6394247
OpenAlexW2916420430

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.