Evidence map›Paper›PMID 30846856›Full record

ReviewNature reviews. Immunology2019

The evolving role of T-bet in resistance to infection.

Gretchen Harms Pritchard, Ross M Kedl, Christopher A Hunter

Open access · greenAbstract readReview
In one paragraph

Review in Nature reviews. Immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 75 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Lung-resident lymphocytes and their roles in respiratory infections and chronic respiratory diseases.Chinese medical journal pulmonary and critical care medicine · 2024
    Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Early immune response toFrontiers in cellular and infection microbiology · 2024
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Gretchen Harms PritchardDepartment of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Ross M KedlDepartment of Immunology and Microbiology, School of Medicine, University of Colorado, Aurora, CO, USA.
Christopher A HunterDepartment of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA. chunter@vet.upenn.edu.
University of Pennsylvania · USUniversity of Colorado Anschutz Medical Campus · US

Funding

Transcriptional regulation of vaccine-elicited and infection-elicited CD8+ T cell responsesR01AI066121 · NIAID · UNIVERSITY OF COLORADO DENVER · PI Ross M Kedl · 2007 to 2026
$7.1M
PARASITOLOGY: MODERN APPROACHEST32AI007532 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI HERBERT, DE'BROSKI R · 1998 to 2022
$5.0M
Molecular and cellular basis of Combined Adjuvant-Elicited Cellular ImmunityR01AI126899 · NIAID · UNIVERSITY OF COLORADO DENVER · PI KEDL, ROSS M · 2016 to 2020
$2.5M
Impact of early T-bet on CD8 T cell effector responsesR01AI125563 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI HUNTER, CHRISTOPHER A · 2016 to 2020
$2.0M
NIAID NIH HHS R01 AI066121NIAID NIH HHS R01 AI125563NIAID NIH HHS R01 AI126899NIAID NIH HHS T32 AI007532
6 · The paper itself

Abstract

The identification of T-bet as a key transcription factor associated with the development of IFNγ-producing CD4

Indexed as

Adaptive ImmunityAnimalsDisease ResistanceHumansImmunity, InnateImmunologic MemoryT-bet Transcription FactorT-Box Domain ProteinsT-LymphocytesEOMES protein, humanT-bet Transcription FactorT-Box Domain Proteins

Identifiers

PMID30846856
PMCPMC7272213
OpenAlexW2919011602

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.