SynthesisJournal of human hypertension2019
Effect of vitamin E supplementation on blood pressure: a systematic review and meta-analysis.
Synthesis in Journal of human hypertension, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 8 syntheses or guidelines pooled it, 58 citations in OpenAlex.
- Effect of vitamin BBMJ open · 2024Pooled it
- The Role of Diet in the Prevention of Hypertension and Management of Blood Pressure: An Umbrella Review of Meta-Analyses of Interventional and Observational Studies.Advances in nutrition (Bethesda, Md.) · 2024Pooled it
- A systematic review with meta-analysis of the relation of aflatoxin B1 to growth impairment in infants/children.BMC pediatrics · 2023Pooled it
- Pooled it
- Fruit and vegetable consumption and the risk of hypertension: a systematic review and meta-analysis of prospective studies.European journal of nutrition · 2023Pooled it
- Pooled it
- Coffee Consumption and Risk of Hypertension in Adults: Systematic Review and Meta-Analysis.Nutrients · 2023Pooled it
- Effects of vitamin C supplementation on essential hypertension: A systematic review and meta-analysis.Medicine · 2020Pooled it
- Identification of Priority Nutrients in the US: Targeting Malnutrition to Address Diet-Related Disease Across the Lifespan.Nutrients · 2025Article
- Dietary vitamin intake and its association with hypertension (HPT) among Malaysian adults.Scientific reports · 2025Article
- Nutrition and Hypertension Researches in 2023: focus on salt intake and blood pressure.Hypertension research : official journal of the Japanese Society of Hypertension · 2025Review
- Association between dietary antioxidant indices and hypertension among Chinese adults.Hypertension research : official journal of the Japanese Society of Hypertension · 2025Article
- A cross-sectional analysis of coffee intake and hypertension prevalence: results from the NHANES 2005-2020.Frontiers in nutrition · 2025Article
- The Role of Oxidative Stress in Hypertension: The Insight into Antihypertensive Properties of Vitamins A, C and E.Antioxidants (Basel, Switzerland) · 2024Review
- The association between blood vitamin E and blood pressure in an adult population with and without diabetes mellitus.Frontiers in endocrinology · 2024Article
- Association between fat-soluble vitamin co-exposure patterns and blood pressure in people with hypertension: a cross-sectional study.Frontiers in nutrition · 2024Article
- Examination of Serum Metabolome Altered by Dietary Carbohydrate, Milk Protein, and Soy Protein Interventions Identified Novel Metabolites Associated with Blood Pressure: The ProBP Trial.Molecular nutrition & food research · 2023Article
- Dietary vitamin E intake and new-onset hypertension.Hypertension research : official journal of the Japanese Society of Hypertension · 2023Article
- Plant bioactive compounds from Mediterranean diet improve risk factors for metabolic syndrome.International journal of food sciences and nutrition · 2023Review
- Association of gamma-tocopherol serum concentrations and blood pressure among adults in the United States: a cross-sectional study.Frontiers in cardiovascular medicine · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although emerging evidence suggests that vitamin E may contribute to blood pressure improvement, the effects of vitamin E on systolic blood pressure (SBP), diastolic blood pressure (DBP), and mean arterial pressure (MAP) are still controversial. The aim was to evaluate the influence of vitamin E on SBP, DBP, and MAP through meta-analysis. We identified all studies that assessed the effect of vitamin E supplementation on SBP, DBP, and MAP from PubMed/Medline, SCOPUS, and Google scholar up to March 2018. Weighted mean differences (WMD) and 95% confidence interval (CI) were expressed as effect size. Pre-specified subgroup analysis was conducted to evaluate potential sources of heterogeneity. Meta-regression analyses were performed to investigate association between blood pressure-lowering effects of vitamin E and duration of follow-up and dose of treatment. Eighteen trials, comprising 839 participants met the eligibility criteria. Results of this study showed that compared to placebo, SBP decreased significantly in vitamin E group (WMD = -3.4 mmHg, 95% CI = -6.7 to -0.11, P < 0.001), with a high heterogeneity across the studies (I
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.