Evidence map›Paper›PMID 30846808›Full record

ArticleScientific reports2019

TACCO, a Database Connecting Transcriptome Alterations, Pathway Alterations and Clinical Outcomes in Cancers.

Po-Hao Chou, Wei-Chao Liao, Kuo-Wang Tsai, Ku-Chung Chen, Jau-Song Yu, Ting-Wen Chen

Abstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
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  4. TMPO-AS1-hsa-let-7b-5p-EZH2-RNA network predicts poor survival in basal-like breast cancer patients.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2025
    Article
  5. Bioinformatics insights intoFrontiers in cell and developmental biology · 2025
    Article
  6. Cancer pharmacoinformatics: Databases and analytical tools.Functional & integrative genomics · 2024
    Review
  7. Article
  8. Article
  9. Article
  10. Involvement ofFrontiers in cell and developmental biology · 2024
    Article
  11. Article
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  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Analysis of Nuclear Encoded Mitochondrial Gene Networks in Cervical Cancer.Asian Pacific journal of cancer prevention : APJCP · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Po-Hao ChouMolecular Medicine Research Center, Chang Gung University, Taoyuan, Taiwan.
Wei-Chao LiaoMolecular Medicine Research Center, Chang Gung University, Taoyuan, Taiwan.
Kuo-Wang TsaiDepartment of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
Ku-Chung ChenDepartment of Biochemistry and Molecular Cell Biology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
Jau-Song YuMolecular Medicine Research Center, Chang Gung University, Taoyuan, Taiwan.
Ting-Wen ChenInstitute of Bioinformatics and Systems Biology, National Chiao Tung University, Hsinchu, Taiwan. afratw@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Because of innumerable cancer sequencing projects, abundant transcriptome expression profiles together with survival data are available from the same patients. Although some expression signatures for prognosis or pathologic staging have been identified from these data, systematically discovering such kind of expression signatures remains a challenge. To address this, we developed TACCO (Transcriptome Alterations in CanCer Omnibus), a database for identifying differentially expressed genes and altered pathways in cancer. TACCO also reveals miRNA cooperative regulations and supports construction of models for prognosis. The resulting signatures have great potential for patient stratification and treatment decision-making in future clinical applications. TACCO is freely available at http://tacco.life.nctu.edu.tw/ .

Indexed as

Databases, FactualTranscriptomeComputational BiologyGene Expression Regulation, NeoplasticHumansInternetMicroRNAsModels, BiologicalNeoplasmsPrognosisRNA, MessengerMicroRNAsRNA, Messenger

Identifiers

PMID30846808
PMCPMC6405743

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.