Evidence map›Paper›PMID 30846699›Full record

ArticleNature communications2019

Bioengineered bacterial vesicles as biological nano-heaters for optoacoustic imaging.

Vipul Gujrati, Jaya Prakash, Jaber Malekzadeh-Najafabadi, Andre Stiel, Uwe Klemm, Gabriele Mettenleiter, Michaela Aichler, Axel Walch, Vasilis Ntziachristos

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 91 papers.

0numbers the graph read from it
0cells of the map it votes in
91citing papers in PubMed
8.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

91 citing papers in PubMed, 207 citations in OpenAlex.

  1. Review
  2. Article
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  4. Review
  5. Review
  6. Frontiers in bacterial outer membrane vesicles: From basic characteristics to cancer therapy.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2026
    Article
  7. Review
  8. Review
  9. Article
  10. Violacein-Loaded Outer Membrane Vesicles fromACS biomaterials science & engineering · 2025
    Article
  11. Article
  12. Review
  13. Bacterial Minicell-Based Biohybrid Sub-micron Swimmers for Targeted Cargo Delivery.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  14. Article
  15. Review
  16. Nanoscale heat generation in a single Si nanowire.Nanophotonics (Berlin, Germany) · 2025
    Article
  17. Review
  18. Review
  19. Article
  20. Article

31 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Vipul GujratiChair of Biological Imaging, TranslaTUM, Technische Universität München, Munich, 81675, Germany.
Jaya PrakashInstitute of Biological and Medical Imaging, Helmholtz Zentrum München, Neuherberg, 85764, Germany.
Jaber Malekzadeh-NajafabadiChair of Biological Imaging, TranslaTUM, Technische Universität München, Munich, 81675, Germany.
Andre StielInstitute of Biological and Medical Imaging, Helmholtz Zentrum München, Neuherberg, 85764, Germany.ORCID http://orcid.org/0000-0001-8675-6797
Uwe KlemmInstitute of Biological and Medical Imaging, Helmholtz Zentrum München, Neuherberg, 85764, Germany.
Gabriele MettenleiterResearch Unit Analytical Pathology, Helmholtz Zentrum München, Neuherberg, 85764, Germany.
Michaela AichlerResearch Unit Analytical Pathology, Helmholtz Zentrum München, Neuherberg, 85764, Germany.
Axel WalchResearch Unit Analytical Pathology, Helmholtz Zentrum München, Neuherberg, 85764, Germany.
Vasilis NtziachristosChair of Biological Imaging, TranslaTUM, Technische Universität München, Munich, 81675, Germany. v.ntziachristos@tum.de.
Helmholtz Zentrum München · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Advances in genetic engineering have enabled the use of bacterial outer membrane vesicles (OMVs) to deliver vaccines, drugs and immunotherapy agents, as a strategy to circumvent biocompatibility and large-scale production issues associated with synthetic nanomaterials. We investigate bioengineered OMVs for contrast enhancement in optoacoustic (photoacoustic) imaging. We produce OMVs encapsulating biopolymer-melanin (OMV

Indexed as

NanoparticlesAnimalsBacterial Outer Membrane ProteinsBioengineeringBiopolymersFemaleHot TemperatureMammary Neoplasms, ExperimentalMelaninsMiceMice, NudeNanotechnologyPhotoacoustic TechniquesTheranostic NanomedicineBacterial Outer Membrane ProteinsBiopolymersMelanins

Identifiers

PMID30846699
PMCPMC6405847
OpenAlexW2920238929

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.