Evidence map›Paper›PMID 30846684›Full record

ArticleNature communications2019

A widely distributed diheme enzyme from Burkholderia that displays an atypically stable bis-Fe(IV) state.

Kimberly Rizzolo, Steven E Cohen, Andrew C Weitz, Madeline M López Muñoz, Michael P Hendrich, Catherine L Drennan, Sean J Elliott

Abstract read
In one paragraph

Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Biochemistry · 2025
    Article
  2. New Frontiers in Nonheme Enzymatic Oxyferryl Species.Chembiochem : a European journal of chemical biology · 2024
    Review
  3. Article
  4. Article
  5. Article
  6. Capturing aBiochemistry · 2023
    Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. A Stable Ferryl Porphyrin at the Active Site of Y463M BthA.Journal of the American Chemical Society · 2020
    Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kimberly RizzoloBoston University, Department of Chemistry, Boston, MA, 02215, USA.
Steven E CohenMassachusetts Institute of Technology, Department of Chemistry, Cambridge, MA, 02139, USA.ORCID http://orcid.org/0000-0002-3193-0740
Andrew C WeitzCarnegie Mellon University, Department of Chemistry, Pittsburgh, PA, 15213, USA.
Madeline M López MuñozBoston University, Department of Chemistry, Boston, MA, 02215, USA.
Michael P HendrichCarnegie Mellon University, Department of Chemistry, Pittsburgh, PA, 15213, USA.
Catherine L DrennanMassachusetts Institute of Technology, Department of Chemistry, Cambridge, MA, 02139, USA.ORCID http://orcid.org/0000-0001-5486-2755
Sean J ElliottBoston University, Department of Chemistry, Boston, MA, 02215, USA. elliott@bu.edu.ORCID http://orcid.org/0000-0003-0096-9551

Funding

Interdepartmental Biotechnology Training ProgramT32GM008334 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI WITTRUP, KARL DANE · 1989 to 2018
$15.2M
Overall EvaluationP41GM103403 · NIGMS · CORNELL UNIVERSITY · PI EALICK, STEVEN E · 2012 to 2017
$14.3M
Metalloenzyme structure, function and assemblyR35GM126982 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI CATHERINE L DRENNAN · 2018 to 2026
$3.4M
Pixel Array Detector for X-ray CrystallographyS10RR029205 · NCRR · CORNELL UNIVERSITY · PI EALICK, STEVEN E · 2010 to 2010
$1.8M
Structure, Function and Diversity in the Bacterial Cytochrome c Peroxidase FamilyR01GM110390 · NIGMS · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI ELLIOTT, SEAN J · 2017 to 2020
$1.3M
NCRR NIH HHS S10 RR029205NIGMS NIH HHS P41 GM103403NIGMS NIH HHS R01 GM110390NIGMS NIH HHS R35 GM126982NIGMS NIH HHS T32 GM008334NIH HHS P41 GM103403NIH HHS R35 GM126982NIH HHS S10 RR029205
6 · The paper itself

Abstract

Bacterial diheme peroxidases represent a diverse enzyme family with functions that range from hydrogen peroxide (H

Indexed as

Bacterial ProteinsBurkholderiaCatalytic DomainCrystallography, X-RayEnzyme StabilityHemeproteinsIronKineticsModels, MolecularOxidation-ReductionPeroxidasesProtein ConformationBacterial ProteinsHemeproteinsIronPeroxidases

Identifiers

PMID30846684
PMCPMC6405878

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.