Evidence map›Paper›PMID 30846544›Full record

ReviewGenetics2019

Developmental Control of the Cell Cycle: Insights from

Edward T Kipreos, Sander van den Heuvel

Open access · bronzeAbstract readReview
In one paragraph

Review in Genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 60 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Notch controls APC/CScience advances · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. A Brief Review on Caenorhabditis elegans Role in Modelling Neurodegenerative Disease.Central nervous system agents in medicinal chemistry · 2025
    Review
  15. Article
  16. Article
  17. Evolution of the Cdk4/6-Cdkn2 system in invertebrates.Genes to cells : devoted to molecular & cellular mechanisms · 2024
    Article
  18. SEM-2/SoxC regulates multiple aspects ofbioRxiv : the preprint server for biology · 2024
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Edward T KipreosDepartment of Cellular Biology, University of Georgia, Athens, Georgia 30602-2607 s.j.l.vandenheuvel@uu.nl ekipreos@uga.edu.ORCID 0000-0001-9650-3558
Sander van den HeuvelDepartment of Biology, Science 4 Life Program, Faculty of Science, University of Utrecht, 3584CH, The Netherlands s.j.l.vandenheuvel@uu.nl ekipreos@uga.edu.ORCID 0000-0001-9015-7463
University of Georgia · USUtrecht University · NL

Funding

Regulation of the cell cycle and signaling by CUL-2 E3 complexesR01GM074212 · NIGMS · UNIVERSITY OF GEORGIA · PI KIPREOS, EDWARD T. · 2007 to 2015
$2.3M
NIGMS NIH HHS R01 GM074212
6 · The paper itself

Abstract

During animal development, a single fertilized egg forms a complete organism with tens to trillions of cells that encompass a large variety of cell types. Cell cycle regulation is therefore at the center of development and needs to be carried out in close coordination with cell differentiation, migration, and death, as well as tissue formation, morphogenesis, and homeostasis. The timing and frequency of cell divisions are controlled by complex combinations of external and cell-intrinsic signals that vary throughout development. Insight into how such controls determine

Indexed as

Cell CycleGene Expression Regulation, DevelopmentalAnimalsCaenorhabditis elegansCell DifferentiationCaenorhabditis eleganscell cyclecell lineageDNA replication licensingproliferationterminal differentiationWormBook

Identifiers

PMID30846544
PMCPMC6404260
OpenAlexW2918966590

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.