Evidence map›Paper›PMID 30846439›Full record

ArticleAJNR. American journal of neuroradiology2019

Metallic Hyperdensity Sign on Noncontrast CT Immediately after Mechanical Thrombectomy Predicts Parenchymal Hemorrhage in Patients with Acute Large-Artery Occlusion.

C Xu, Y Zhou, R Zhang, Z Chen, W Zhong, X Gong, X Ding, M Lou

Open access · hybridAbstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

C XuFrom the Departments of Neurology (C.X., Y.Z., R.Z., Z.C., W.Z, X.G., M.L.).ORCID 0000-0002-4842-4086
Y ZhouFrom the Departments of Neurology (C.X., Y.Z., R.Z., Z.C., W.Z, X.G., M.L.).ORCID 0000-0003-3577-4527
R ZhangFrom the Departments of Neurology (C.X., Y.Z., R.Z., Z.C., W.Z, X.G., M.L.).ORCID 0000-0003-1203-7540
Z ChenFrom the Departments of Neurology (C.X., Y.Z., R.Z., Z.C., W.Z, X.G., M.L.).ORCID 0000-0003-4937-6749
W ZhongFrom the Departments of Neurology (C.X., Y.Z., R.Z., Z.C., W.Z, X.G., M.L.).ORCID 0000-0002-4775-7778
X GongFrom the Departments of Neurology (C.X., Y.Z., R.Z., Z.C., W.Z, X.G., M.L.).ORCID 0000-0002-0047-1246
X DingRadiology (X.D.), the Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou, China.ORCID 0000-0002-5528-566X
M LouFrom the Departments of Neurology (C.X., Y.Z., R.Z., Z.C., W.Z, X.G., M.L.) lm99@zju.edu.cn.ORCID 0000-0002-6627-064X
ZTE (United States) · USSecond Affiliated Hospital of Zhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeParenchymal hemorrhage is a severe complication following mechanical recanalization in patients with acute ischemic stroke with large-vessel occlusion. This study aimed to assess whether the metallic hyperdensity sign on noncontrast CT performed immediately after mechanical thrombectomy can predict parenchymal hemorrhage at 24 hours. MATERIALS AND

methodsWe included consecutive patients with acute ischemic stroke with large-vessel occlusion who underwent noncontrast CT immediately after mechanical thrombectomy between January 2014 and September 2018. The metallic hyperdensity sign was defined as a nonpetechial intracerebral hyperdense lesion (diameter, ≥1 cm) in the basal ganglia and a maximum CT density of >90 HU. The sensitivity, specificity, and positive and negative predictive values of the metallic hyperdensity sign in predicting parenchymal hemorrhage were calculated.

resultsA total of 198 patients were included. The metallic hyperdensity sign was found in 59 (29.7%) patients, and 51 (25.7%) patients had parenchymal hemorrhage at 24 hours. Patients with the metallic hyperdensity sign are more likely to have parenchymal hemorrhage than those without it (76.3% versus 4.3%,

conclusionsThe presence of the metallic hyperdensity sign on noncontrast CT performed immediately after mechanical thrombectomy in patients with large-vessel occlusion could predict the occurrence of parenchymal hemorrhage at 24 hours, which might be helpful in postinterventional management within 24 hours after mechanical thrombectomy.

Indexed as

AgedAged, 80 and overCerebral HemorrhageFemaleHumansMaleMiddle AgedRetrospective StudiesSensitivity and SpecificityStrokeThrombectomyTomography, X-Ray Computed

Identifiers

PMID30846439
PMCPMC7048513
OpenAlexW2920525773

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.