ArticleAJNR. American journal of neuroradiology2019
CT and Multimodal MR Imaging Features of Embryonal Tumors with Multilayered Rosettes in Children.
Article in AJNR. American journal of neuroradiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Imaging of Pineal Region Masses.Advances and technical standards in neurosurgery · 2026Review
- Rare and aggressive: A case of embryonal tumor with multilayered rosettes (ETMR) in a young child.Radiology case reports · 2025Article
- CNS Embryonal Tumor with PLAGL Amplification, a New Tumor in Children and Adolescents: Insights from a Comprehensive MRI Analysis.AJNR. American journal of neuroradiology · 2025Article
- Supra-tentorial Ependymomas with ZFTA Fusion, YAP1 Fusion, and Astroblastomas, MN1-altered: Characteristic Imaging Features.Clinical neuroradiology · 2024Article
- Approaches to supratentorial brain tumours in children.Neuroradiology · 2024Review
- Imaging of supratentorial intraventricular masses in children: a pictorial review-part 2.Neuroradiology · 2024Review
- Imaging characterization of paediatric tumours with the neurotrophic tyrosine receptor kinase fusion transcript.The British journal of radiology · 2024Article
- Imaging of supratentorial ependymomas with radio-pathological correlation.Exploration of targeted anti-tumor therapy · 2024Article
- Brain and Spinal Cord Tumors of Embryonic Origin.Advances in experimental medicine and biology · 2023Article
- Embryonal tumor with multilayered rosettes: a report of a rare case.BJR case reports · 2022Article
- Imaging Features with Histopathologic Correlation of CNS High-Grade Neuroepithelial Tumors with aAJNR. American journal of neuroradiology · 2022Article
- Pre- and Post-Treatment Imaging of Primary Central Nervous System Tumors in the Molecular and Genetic Era.Korean journal of radiology · 2021Review
- Intradural Pediatric Spinal Tumors: An Overview from Imaging to Novel Molecular Findings.Diagnostics (Basel, Switzerland) · 2021Review
- Embryonal tumor with multilayered rosettes: Overview of diagnosis and therapy.Neuro-oncology advancesArticle
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Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeEmbryonal tumors with multilayered rosettes, C19MC-altered, are brain tumors occurring in young children, which were clearly defined in the 2016 World Health Organization classification of central nervous system neoplasms. Our objective was to describe the multimodal imaging characteristics of this new entity. MATERIALS AND
methodsWe performed a retrospective monocentric review of embryonal brain tumors and looked for embryonal tumors with multilayered rosettes with confirmed C19MC alteration. We gathered morphologic imaging data, as well as DWI and PWI data (using arterial spin-labeling and DSC).
resultsWe included 16 patients with a median age of 2 years 8 months. Tumors were both supratentorial (56%, 9/16) and infratentorial (44%, 7/16). Tumors were large (median diameter, 59 mm; interquartile range, 48-71 mm), with absent (75%, 12/16) or minimal (25%, 4/16) peritumoral edema. Enhancement was absent (20%, 3/15) or weak (73%, 11/15), whereas intratumoral macrovessels were frequently seen (94%, 15/16) and calcifications were present in 67% (10/15). Diffusion was always restricted, with a minimal ADC of 520 mm
conclusionsEmbryonal tumors with multilayered rosettes, C19MC-altered, have characteristic imaging features that could help in the diagnosis of this rare tumor in young children.
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