Evidence map›Paper›PMID 30845766›Full record

ArticlePharmaceutics2019

Physiologically-Based Pharmacokinetic Modeling for Drug-Drug Interactions of Procainamide and

Yoo-Seong Jeong, Anusha Balla, Kwang-Hoon Chun, Suk-Jae Chung, Han-Joo Maeng

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Transporters and drug secretion into human breast milk.Expert opinion on drug metabolism & toxicology · 2025
    Review
  3. Investigation ofPharmaceutics · 2023
    Article
  4. Effects of 1α,25-dihydroxyvitamin DJournal of pharmaceutical investigation · 2022
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yoo-Seong JeongCollege of Pharmacy, Seoul National University, Seoul 08826, Korea. jus2401@snu.ac.kr.
Anusha BallaCollege of Pharmacy, Gachon University, Incheon 21936, Korea. aanushaballa@gmail.com.
Kwang-Hoon ChunCollege of Pharmacy, Gachon University, Incheon 21936, Korea. khchun@gachon.ac.kr.
Suk-Jae ChungCollege of Pharmacy, Seoul National University, Seoul 08826, Korea. sukjae@snu.ac.kr.
Han-Joo MaengCollege of Pharmacy, Gachon University, Incheon 21936, Korea. hjmaeng@gachon.ac.kr.
Gachon University · KRSeoul National University · KR

Funding

Basic Science Research Program through the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIT) 2016R1D1A1B03931470
6 · The paper itself

Abstract

Previous observations demonstrated that cimetidine decreased the clearance of procainamide (PA) and/or

Indexed as

cimetidineN-acetylprocainamidephysiologically-based pharmacokinetic modeling for drug-drug interactionsprocainamiderat multidrug and toxin extrusion protein 1rat organic cation transporter 2

Identifiers

PMID30845766
PMCPMC6470842
OpenAlexW2920466331

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.