Evidence map›Paper›PMID 30845683›Full record

ArticleNanomaterials (Basel, Switzerland)2019

Sterilization Procedure for Temperature-Sensitive Hydrogels Loaded with Silver Nanoparticles for Clinical Applications.

Diana Rafael, Fernanda Andrade, Francesc Martinez-Trucharte, Jana Basas, Joaquín Seras-Franzoso, Marta Palau, Xavier Gomis, Marc Pérez-Burgos, Alberto Blanco, Alba López-Fernández and 5 more

Abstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

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  15. Autoclaving of Poloxamer 407 hydrogel and its use as a drug delivery vehicle.Journal of biomedical materials research. Part B, Applied biomaterials · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Diana RafaelDrug Delivery and Targeting Group, Molecular Biology and Biochemistry Research Centre for Nanomedicine (CIBBIM-Nanomedicine), Vall d'Hebron Institut de Recerca (VHIR), Universitat Autònoma de Barcelona (UAB), 08035 Barcelona, Spain. diana.fernandes_de_so@vhir.org.
Fernanda AndradeDrug Delivery and Targeting Group, Molecular Biology and Biochemistry Research Centre for Nanomedicine (CIBBIM-Nanomedicine), Vall d'Hebron Institut de Recerca (VHIR), Universitat Autònoma de Barcelona (UAB), 08035 Barcelona, Spain. fernanda.silva@vhir.org.ORCID 0000-0002-4947-2346
Francesc Martinez-TrucharteDrug Delivery and Targeting Group, Molecular Biology and Biochemistry Research Centre for Nanomedicine (CIBBIM-Nanomedicine), Vall d'Hebron Institut de Recerca (VHIR), Universitat Autònoma de Barcelona (UAB), 08035 Barcelona, Spain. francesc.martinez@vhir.org.
Jana BasasAntimicrobial Resistance Laboratory, Vall d'Hebron Research Institute (VHIR), Department of Infectious Diseases, Hospital Universitari Vall d'Hebron, 08035 Barcelona, Spain. jana.basas@vhir.org.
Joaquín Seras-FranzosoDrug Delivery and Targeting Group, Molecular Biology and Biochemistry Research Centre for Nanomedicine (CIBBIM-Nanomedicine), Vall d'Hebron Institut de Recerca (VHIR), Universitat Autònoma de Barcelona (UAB), 08035 Barcelona, Spain. joaquin.seras@vhir.org.ORCID 0000-0002-7893-4773
Marta PalauAntimicrobial Resistance Laboratory, Vall d'Hebron Research Institute (VHIR), Department of Infectious Diseases, Hospital Universitari Vall d'Hebron, 08035 Barcelona, Spain. marta.palau@vhir.org.ORCID 0000-0002-4567-9868
Xavier GomisAntimicrobial Resistance Laboratory, Vall d'Hebron Research Institute (VHIR), Department of Infectious Diseases, Hospital Universitari Vall d'Hebron, 08035 Barcelona, Spain. xavier.gomis@vhir.org.
Marc Pérez-BurgosDrug Delivery and Targeting Group, Molecular Biology and Biochemistry Research Centre for Nanomedicine (CIBBIM-Nanomedicine), Vall d'Hebron Institut de Recerca (VHIR), Universitat Autònoma de Barcelona (UAB), 08035 Barcelona, Spain. marcpburgos@gmail.com.ORCID 0000-0001-9754-8301
Alberto BlancoOrthopedic Surgery Department, Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona (UAB), 08035 Barcelona, Spain. dr.blancosevilla@gmail.com.
Alba López-FernándezMusculoskeletal Tissue Engineering Group, Vall d'Hebron Research Institute (VHIR), Universitat Autònoma de Barcelona (UAB), Passeig de la Vall d'Hebron 129-139, 08035 Barcelona, Spain. alba.lopez@vhir.org.ORCID 0000-0001-6072-0294
Roberto VélezOrthopedic Surgery Department, Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona (UAB), 08035 Barcelona, Spain. robertovelez1@gmail.com.ORCID 0000-0001-8917-6050
Ibane AbasoloDrug Delivery and Targeting Group, Molecular Biology and Biochemistry Research Centre for Nanomedicine (CIBBIM-Nanomedicine), Vall d'Hebron Institut de Recerca (VHIR), Universitat Autònoma de Barcelona (UAB), 08035 Barcelona, Spain. ibane.abasolo@vhir.org.
Màrius AguirreOrthopedic Surgery Department, Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona (UAB), 08035 Barcelona, Spain. marius.aguirre@vhir.org.
Joan GavaldàAntimicrobial Resistance Laboratory, Vall d'Hebron Research Institute (VHIR), Department of Infectious Diseases, Hospital Universitari Vall d'Hebron, 08035 Barcelona, Spain. joan.gavalda@vhir.org.
Simó SchwartzDrug Delivery and Targeting Group, Molecular Biology and Biochemistry Research Centre for Nanomedicine (CIBBIM-Nanomedicine), Vall d'Hebron Institut de Recerca (VHIR), Universitat Autònoma de Barcelona (UAB), 08035 Barcelona, Spain. simo.schwartz@vhir.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hydrogels (HG) have recognized benefits as drug delivery platforms for biomedical applications. Their high sensitivity to sterilization processes is however one of the greatest challenges regarding their clinical translation. Concerning infection diseases, prevention of post-operatory related infections is crucial to ensure appropriate patient recovery and good clinical outcomes. Silver nanoparticles (AgNPs) have shown good antimicrobial properties but sustained release at the right place is required. Thus, we produced and characterized thermo-sensitive HG based on Pluronic

Indexed as

anti-bacterial agentschirurgic applicationshydrogelspoloxamerpost-operative infectionssilver nanoparticlessterilizationXDR strains

Identifiers

PMID30845683
PMCPMC6474025

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.