Evidence map›Paper›PMID 30845635›Full record

ArticleVeterinary sciences2019

Intracoronary Gene Delivery of the Cytoprotective Factor Vascular Endothelial Growth Factor-B

Paola Paradies, Lucia Carlucci, Felix Woitek, Francesco Staffieri, Luca Lacitignola, Luigi Ceci, Daniela Romano, Mariateresa Sasanelli, Lorena Zentilin, Mauro Giacca and 3 more

Open access · goldAbstract read
In one paragraph

Article in Veterinary sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Cardiac revascularization: state of the art and perspectives.Vascular biology (Bristol, England) · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Paola ParadiesDepartment of Emergency and Organ Transplantation, Section of Veterinary Clinics and Animal Production; University of Bari, 70010 Bari; Italy. paola.paradies@uniba.it.ORCID 0000-0001-8820-1453
Lucia CarlucciInstitute of Life Sciences, Scuola Superiore Sant'Anna, 56100 Pisa, Italy. lucia.carlucci3@gmail.com.
Felix WoitekHeart Center, Dresden at the Technical University of Dresden, 01067 Dresden, Germany. felix.woitek@mailbox.tu-dresden.de.
Francesco StaffieriDepartment of Emergency and Organ Transplantation, Section of Veterinary Clinics and Animal Production; University of Bari, 70010 Bari; Italy. francesco.staffieri@uniba.it.ORCID 0000-0002-2085-376X
Luca LacitignolaDepartment of Emergency and Organ Transplantation, Section of Veterinary Clinics and Animal Production; University of Bari, 70010 Bari; Italy. luca.lacitignola@uniba.it.
Luigi CeciDepartment of Emergency and Organ Transplantation, Section of Veterinary Clinics and Animal Production; University of Bari, 70010 Bari; Italy. luigi.ceci@uniba.it.
Daniela RomanoDepartment of Emergency and Organ Transplantation, Section of Veterinary Clinics and Animal Production; University of Bari, 70010 Bari; Italy. dadda.romano@gmail.com.
Mariateresa SasanelliDepartment of Emergency and Organ Transplantation, Section of Veterinary Clinics and Animal Production; University of Bari, 70010 Bari; Italy. mariateresa.sasanelli@uniba.it.
Lorena ZentilinMolecular Medicine Laboratory, International Centre for Genetic Engineering and Biotechnology (ICGEB), 34149 Trieste, Italy. lorena@icgeb.org.ORCID 0000-0001-7514-8155
Mauro GiaccaMolecular Medicine Laboratory, International Centre for Genetic Engineering and Biotechnology (ICGEB), 34149 Trieste, Italy. giacca@icgeb.org.
Stefano SalvadoriCNR, Institute of Clinical Physiology, Area della Ricerca, 56121 Pisa, Italy. stefsa@ifc.cnr.it.ORCID 0000-0002-1266-3931
Antonio CrovaceDepartment of Emergency and Organ Transplantation, Section of Veterinary Clinics and Animal Production; University of Bari, 70010 Bari; Italy. antonio.crovace@uniba.it.
Fabio A RecchiaInstitute of Life Sciences, Scuola Superiore Sant'Anna, 56100 Pisa, Italy. f.recchia@santannapisa.it.
University of Bari Aldo Moro · ITInternational Centre for Genetic Engineering and Biotechnology · ITScuola Superiore Sant'Anna · ITIstituto di Fisiologia Clinica · ITTechnische Universität Dresden · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dilated cardiomyopathy (DCM) is a myocardial disease of dogs and humans characterized by progressive ventricular dilation and depressed contractility and it is a frequent cause of heart failure. Conventional pharmacological therapy cannot reverse the progression of the disease and, in humans, cardiac transplantation remains the only option during the final stages of heart failure. Cytoprotective gene therapy with vascular endothelial growth factor-B

Indexed as

clinical studydogsintracoronary cytoprotective gene therapy

Identifiers

PMID30845635
PMCPMC6466215
OpenAlexW2918706504

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.