Evidence map›Paper›PMID 30845328›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2019

Accelerating Typhoid Conjugate Vaccine Introduction: What Can Be Learned From Prior New Vaccine Introduction Initiatives?

Leslie P Jamka, Kenneth W Simiyu, Adwoa D Bentsi-Enchill, Aziza J Mwisongo, Helen Matzger, Anthony A Marfin, Andrew J Pollard, Kathleen M Neuzil

Open access · hybridAbstract read
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. The Time is Now to Control Typhoid.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Leslie P JamkaCenter for Vaccine Development and Global Health at the University of Maryland School of Medicine, Baltimore, MD.
Kenneth W SimiyuCenter for Vaccine Development and Global Health at the University of Maryland School of Medicine, Baltimore, MD.
Adwoa D Bentsi-EnchillDepartment of Immunization, Vaccines and Biologicals, World Health Organization, Geneva, Switzerland.
Aziza J MwisongoCenter for Vaccine Innovation and Access, PATH, Seattle, Washington.
Helen MatzgerDepartment of Immunization, Vaccines and Biologicals, World Health Organization, Geneva, Switzerland.
Anthony A MarfinCenter for Vaccine Innovation and Access, PATH, Seattle, Washington.
Andrew J PollardOxford Vaccine Group, Department of Paediatrics, University of Oxford, and the NIHR Oxford Biomedical Research Centre, Oxford, United Kingdom.
Kathleen M NeuzilCenter for Vaccine Development and Global Health at the University of Maryland School of Medicine, Baltimore, MD.
University of Maryland, Baltimore · USProgram for Appropriate Technology in Health · USWorld Health Organization · CHUniversity of Oxford · GB

Funding

World Health Organization 001
6 · The paper itself

Abstract

The health consequences of typhoid, including increasing prevalence of drug-resistant strains, can stress healthcare systems. While vaccination is one of the most successful and cost-effective health interventions, vaccine introduction can take years and require considerable effort. The Typhoid Vaccine Acceleration Consortium (TyVAC) employs an integrated, proactive approach to accelerate the introduction of a new typhoid conjugate vaccine to reduce the burden of typhoid in countries eligible for support from Gavi, the Vaccine Alliance. TyVAC and its partners are executing a plan, informed by prior successful vaccine introductions, and tailored to the nuances of typhoid disease and the typhoid conjugate vaccine. The iterative process detailed herein summarizes the strategy and experience gained from the first 2 years of the project.

Indexed as

Immunization ProgramsAfricaAsiaGlobal HealthHumansTyphoid FeverTyphoid-Paratyphoid VaccinesVaccinationVaccines, ConjugateWorld Health OrganizationTyphoid-Paratyphoid VaccinesVaccines, ConjugateAfricaAsiaintroductiontyphoid conjugate vaccineTyVAC

Identifiers

PMID30845328
PMCPMC6405264
OpenAlexW2920974691

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.