Evidence map›Paper›PMID 30844643›Full record

ArticleRedox biology2019

Vascular peroxidase 1 is a novel regulator of cardiac fibrosis after myocardial infarction.

Zhaoya Liu, Qian Xu, Qixin Yang, Jing Cao, Cong Wu, Huihui Peng, Xinyi Zhang, Jia Chen, Guangjie Cheng, Yueheng Wu and 2 more

Erratum issuedOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Redox biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 48 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Zhaoya LiuDepartment of Cardiovascular Medicine, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Qian XuDepartment of Cardiovascular Medicine, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Qixin YangDepartment of Cardiovascular Medicine, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Jing CaoDepartment of Cardiovascular Medicine, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Cong WuDepartment of Cardiovascular Medicine, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Huihui PengDepartment of Cardiovascular Medicine, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Xinyi ZhangDepartment of Cardiovascular Medicine, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Jia ChenDepartment of Humanistic Nursing, Xiangya Nursing School, Central South University, Changsha, Hunan, China.
Guangjie ChengDivision of Pulmonary, Allergy & Critical Care Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, USA.
Yueheng WuDepartment of Cardiovascular Medicine, Guangdong General Hospital, Guangzhou, Guangdong China.
Ruizheng ShiDepartment of Cardiovascular Medicine, Xiangya Hospital, Central South University, Changsha, Hunan, China; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan, China. Electronic address: xyshiruizheng@csu.edu.cn.
Guogang ZhangDepartment of Cardiovascular Medicine, Xiangya Hospital, Central South University, Changsha, Hunan, China; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan, China. Electronic address: zhangguogang@csu.edu.cn.
Xiangya Hospital Central South University · CNCentral South University · CNGuangdong General Hospital · CNUniversity of Alabama at Birmingham · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac fibrosis is the most important mechanism contributing to cardiac remodeling after myocardial infarction (MI). VPO1 is a heme enzyme that uses hydrogen peroxide (H

Indexed as

AnimalsBiomarkersCardiomyopathiesCell DifferentiationCell MovementCell ProliferationCollagen Type IDisease Models, AnimalFibrosisFluorescent Antibody TechniqueGene ExpressionHeart Function TestsHumansImmunohistochemistryMaleMiceBiomarkersCollagen Type IPeroxidasesPeroxidasinPXDN protein, humanCardiac fibroblastsCardiac fibrosisCardiac remodelingMyocardial infarctionVascular peroxidase1

Identifiers

PMID30844643
PMCPMC6402381
OpenAlexW2920303423

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.