Evidence map›Paper›PMID 30844145›Full record

ReviewThe Kaohsiung journal of medical sciences2019

An overview of microbiome based strategies on anti-obesity.

Cherng-Shyang Chang, Jhen-Wei Ruan, Cheng-Yuan Kao

Open access · goldAbstract readReview
In one paragraph

Review in The Kaohsiung journal of medical sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Anti-obesity peptides from food: Production, evaluation, sources, and commercialization.Comprehensive reviews in food science and food safety · 2025
    Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. An overview of microbiome based strategies on anti-obesity.The Kaohsiung journal of medical sciences · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Cherng-Shyang ChangImmunology Research Center, National Health Research Institutes, Zhunan, Miaoli, Taiwan.
Jhen-Wei RuanDepartment of Medical Laboratory Science and Biotechnology, National Cheng Kung University, Tainan, Taiwan.
Cheng-Yuan KaoImmunology Research Center, National Health Research Institutes, Zhunan, Miaoli, Taiwan.
National Health Research Institutes · TWNational Cheng Kung University · TW

Funding

Ministry of Science and Technology, Taiwan (MOST) 104-2320-B-400-019-MY3Ministry of Science and Technology, Taiwan (MOST) 106-2628-B-400-001-MY3National Health Research Institutes (NHRI) IM-107-PP-04
6 · The paper itself

Abstract

With the significant global obesity epidemic and emerging strong scientific evidence that connected gut microbiota to obesity, intervening obesity by targeting gut microbiota has become a trendy strategy. Particularly the application of probiotics has become remarkably popular because of their expected association with gut microbiota modulation. Although there are many literatures on the effects of probiotics in obese animal models, most of them reported the effects of probiotic bacteria on metabolic indications with limited information on anti-obesity itself. Besides, some probiotics have been shown to reduce certain metabolic symptoms but they failed to achieve weight loss. This report reviewed the current literatures on the anti-obesity effects of next-generation probiotics in various animal obesity models and discussed the beneficial potential of fecal microbiota transplantation in treating obesity in humans. The purpose of this article is to help guide further research improve the probiotic bacteria experiments in more precise animal obesity models by standardizing the anti-obesogenesis, obesity control, and treatment assays and hopefully the evidence-based investigations on harnessing gut microbiota through next-generation probiotics or fecal microbiota transplantation will develop new interventions to promote and achieve anti-obesity.

Indexed as

Gastrointestinal MicrobiomeAnimalsAnti-Obesity AgentsFecal Microbiota TransplantationHumansObesityProbioticsAnti-Obesity Agentsmicrobiomeobesityprobiotics

Identifiers

PMID30844145
PMCPMC11900707
OpenAlexW2922245500

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.