Evidence map›Paper›PMID 30844141›Full record

ArticleThe Kaohsiung journal of medical sciences2019

Topical administration of hydroethanolic extract of Lawsonia inermis (henna) accelerates excisional wound healing process by reducing tissue inflammation and amplifying glucose uptake.

Amin Daemi, Mohammad R Farahpour, Ahmad Oryan, Sirvan Karimzadeh, Ehsan Tajer

Open access · goldAbstract read
In one paragraph

Article in The Kaohsiung journal of medical sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
4.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 48 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Phytosynthesis of Eco-Friendly Silver Nanoparticles UsingJournal of pharmacy & bioallied sciences · 2024
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  5. Article
  6. Antiulcerogenic and healing activity of hecogenin acetate in rodents.Naunyn-Schmiedeberg's archives of pharmacology · 2023
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Synergistic Antimicrobial Effect ofInfection and drug resistance · 2022
    Article
  13. Accelerative effect of topicalPharmaceutical biology · 2021
    Article
  14. Wound healing activity of the hydroethanolic extract of the leaves ofJournal of traditional and complementary medicine · 2021
    Article
  15. Effect of White Tea (World journal of plastic surgery · 2021
    Article
  16. Topical application ofPharmaceutical biology · 2019
    Article
  17. Article
  18. Article
  19. Protective effect of Henna (Avicenna journal of phytomedicine
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Amin DaemiDepartment of Biology, Miandoab Branch, Islamic Azad University, Miandoab, Iran.
Mohammad R FarahpourYoung Researchers and Elite Club, Urmia Branch, Islamic Azad University, Urmia, Iran.
Ahmad OryanDepartment of Pathology, School of Veterinary Medicine, Shiraz University, Shiraz, Iran.
Sirvan KarimzadehFaculty of Veterinary Medicine, Urmia Branch, Islamic Azad University, Urmia, Iran.
Ehsan TajerFaculty of Veterinary Medicine, Urmia Branch, Islamic Azad University, Urmia, Iran.
Islamic Azad University of Urmia · IRIslamic Azad University of Marand · IRShiraz University · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several studies have reported the beneficial effects of Lawsonia inermis on wound healing, but the mechanism of action is still unknown. This study aimed to investigate the effectiveness of a new ointment formulation of hydroethanolic extract leaves of L. inermis on wound healing by gene expression of glucose transporter-1 (Glut-1) and insulin-like growth factor I (Igf-1) in Wistar rats. The animals were topically treated with different doses of L. inermis. An experimentally induced circular excisional wound model of 314 mm

Indexed as

Administration, TopicalAlkaline PhosphataseAntioxidantsCarbohydratesEpidermisEthanolFibroblastsFlavonoidsGlucoseGlucose Transporter Type 1InflammationInsulin-Like Growth Factor IKeratinocytesLawsonia PlantPhenolsPlant ExtractsAlkaline PhosphataseAntioxidantsCarbohydratesEthanolFlavonoidsGlucoseGlucose Transporter Type 1Insulin-Like Growth Factor IPhenolsPlant ExtractsRNA, MessengerWatercollagen depositionexcisional wound healingglucose uptakeLawsonia inermis (henna)tissue inflammation

Identifiers

PMID30844141
PMCPMC11900754
OpenAlexW2921113370

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.