Evidence map›Paper›PMID 30844130›Full record

ArticleColorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland2019

Transanal total mesorectal excision: how are we doing so far?

C L Sparreboom, N Komen, D Rizopoulos, H L van Westreenen, P G Doornebosch, J W T Dekker, A G Menon, J B Tuynman, F Daams, D Lips and 5 more

Open access · hybridAbstract readComparative StudyMulticenter Study
In one paragraph

Article in Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 6 pooled it
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 6 syntheses or guidelines pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  4. Pooled it
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  6. Pooled it
  7. Observational
  8. Review
  9. Article
  10. Article
  11. [TaTME is an experimental procedure].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 10 institutions in 2 countries.

C L SparreboomDepartment of Surgery, Erasmus University Medical Center, Rotterdam, The Netherlands.ORCID https://orcid.org/0000-0002-4606-6895
N KomenDepartment of Surgery, University Hospital Antwerp, Edegem, Belgium.
D RizopoulosDepartment of Biostatistics, Erasmus University Medical Center, Rotterdam, The Netherlands.
H L van WestreenenDepartment of Surgery, Isala, Zwolle, The Netherlands.
P G DoorneboschDepartment of Surgery, IJsselland Ziekenhuis, Capelle aan den IJssel, The Netherlands.
J W T DekkerDepartment of Surgery, Reinier de Graaf Gasthuis, Delft, The Netherlands.
A G MenonDepartment of Surgery, IJsselland Ziekenhuis, Capelle aan den IJssel, The Netherlands.
J B TuynmanDepartment of Surgery, VU University Medical Center, Amsterdam, The Netherlands.
F DaamsDepartment of Surgery, VU University Medical Center, Amsterdam, The Netherlands.
D LipsDepartment of Surgery, Jeroen Bosch Ziekenhuis, Hertogenbosch, The Netherlands.
W M U van GrevensteinDepartment of Surgery, Universitair Medisch Centrum Utrecht, Utrecht, The Netherlands.
T M KarstenDepartment of Surgery, Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands.
J F LangeDepartment of Surgery, Erasmus University Medical Center, Rotterdam, The Netherlands.
A D'HooreDepartmenf of Abdominal Surgery, University Hospital Leuven, Leuven, Belgium.
A M WolthuisDepartmenf of Abdominal Surgery, University Hospital Leuven, Leuven, Belgium.ORCID https://orcid.org/0000-0002-1200-387X
Erasmus MC · NLAmsterdam UMC Location Vrije Universiteit Amsterdam · NLIJsselland Ziekenhuis · NLKU Leuven · BEAntwerp University Hospital · BEIsala · NLJeroen Bosch Ziekenhuis · NLOLVG · NLReinier de Graaf Hospital · NLUniversity Medical Center Utrecht · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThis subgroup analysis of a prospective multicentre cohort study aims to compare postoperative morbidity between transanal total mesorectal excision (TaTME) and laparoscopic total mesorectal excision (LaTME).

methodThe study was designed as a subgroup analysis of a prospective multicentre cohort study. Patients undergoing TaTME or LaTME for rectal cancer were selected. All patients were followed up until the first visit to the outpatient clinic after hospital discharge. Postoperative complications were classified according to the Clavien-Dindo classification and the comprehensive complication index (CCI). Propensity score matching was performed.

resultsIn total, 220 patients were selected from the overall prospective multicentre cohort study. After propensity score matching, 48 patients from each group were compared. The median tumour height for TaTME was 10.0 cm (6.0-10.8) and for LaTME was 9.5 cm (7.0-12.0) (P = 0.459). The duration of surgery and anaesthesia were both significantly longer for TaTME (221 vs 180 min, P < 0.001, and 264 vs 217 min, P < 0.001). TaTME was not converted to laparotomy whilst surgery in five patients undergoing LaTME was converted to laparotomy (0.0% vs 10.4%, P = 0.056). No statistically significant differences were observed for Clavien-Dindo classification, CCI, readmissions, reoperations and mortality.

conclusionThe study showed that TaTME is a safe and feasible approach for rectal cancer resection. This new technique obtained similar postoperative morbidity to LaTME.

Indexed as

AgedFemaleHumansLaparoscopyMaleMiddle AgedPostoperative ComplicationsProctectomyPropensity ScoreProspective StudiesRectal NeoplasmsTransanal Endoscopic SurgeryTreatment Outcomelaparoscopicminimal invasive surgeryrectal cancertransanal

Identifiers

PMID30844130
PMCPMC6850385
OpenAlexW2921081022

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.