SynthesisRevista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)
Brazilian guidelines for the management of psychomotor agitation. Part 2. Pharmacological approach.
Synthesis in Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Brazilian Psychiatric Association guidelines for the management of suicidal behavior. Part 2. Screening, intervention, and prevention.Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)Pooled it
- A Comprehensive Understanding of Psychomotor Agitation: From Causes to Hospital Care.Current neuropharmacology · 2025Review
- Development of a Clinical Guideline for Suicide Prevention in Psychiatric Patients Based on the ADAPTE Methodology.Psychiatry investigation · 2024Article
- Effectiveness of pharmacological treatments for severe agitation in real-world emergency settings: protocol of individual-participant-data network meta-analysis.Systematic reviews · 2024Article
- Prescription Patterns of Intramuscular Medication for Psychomotor Agitation: A Survey of Italian Psychiatrists.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2024Article
- Interfaces between oncology and psychiatry.Revista da Associacao Medica Brasileira (1992) · 2024Article
- Article
- Clinical Practice Guidelines for Assessment and Management of Aggressive and Assaultive Behaviour.Indian journal of psychiatry · 2023Article
- Editorial: Current challenges and evidence-based medicine in psychiatric emergencies.Frontiers in psychiatry · 2023Article
- Puerperal psychosis: an update.Revista da Associacao Medica Brasileira (1992) · 2023Article
- The Management of Psychomotor Agitation Associated with Schizophrenia or Bipolar Disorder: A Brief Review.International journal of environmental research and public health · 2021Review
- Which Emergent Medication Should I Give Next? Repeated Use of Emergent Medications to Treat Acute Agitation.Frontiers in psychiatry · 2021Review
- The Management of Psychiatric Emergencies in Situations of Public Calamity.Frontiers in psychiatry · 2021Review
- Overcoming the Use of Mechanical Restraints in Psychiatry: A New Challenge in the Everyday Clinical Practice at the Time of COVID-19.Journal of clinical medicine · 2020Article
- The Impact of Mental Illness Stigma on Psychiatric Emergencies.Frontiers in psychiatry · 2020Article
- Brazilian guidelines for the management of psychomotor agitation. Part 1. Non-pharmacological approach.Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)Article
- How challenging is to manage agitated patients?Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo present the essential guidelines for pharmacological management of patients with psychomotor agitation in Brazil.
methodsThis is a systematic review of articles retrieved from the MEDLINE (PubMed), Cochrane Database of Systematic Reviews, and SciELO databases published from 1997 to 2017. Other relevant articles in the literature were also used to develop these guidelines. The search strategy used structured questions formulated using the PICO model, as recommended by the Guidelines Project of the Brazilian Medical Association. Recommendations were summarized according to their level of evidence, which was determined using the Oxford Centre for Evidence-based Medicine system and critical appraisal tools.
resultsOf 5,362 articles retrieved, 1,731 abstracts were selected for further reading. The final sample included 74 articles that met all inclusion criteria. The evidence shows that pharmacologic treatment is indicated only after non-pharmacologic approaches have failed. The cause of the agitation, side effects of the medications, and contraindications must guide the medication choice. The oral route should be preferred for drug administration; IV administration must be avoided. All subjects must be monitored before and after medication administration.
conclusionIf non-pharmacological strategies fail, medications are needed to control agitation and violent behavior. Once medicated, the patient should be monitored until a tranquil state is possible without excessive sedation. SYSTEMATIC REVIEW REGISTRY NUMBER: CRD42017054440.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.