Evidence map›Paper›PMID 30843708›Full record

ArticleDevelopmental psychology2019

Parenting and prenatal risk as moderators of genetic influences on conduct problems during middle childhood.

Kristine Marceau, Emily Rolan, Leslie D Leve, Jody M Ganiban, David Reiss, Daniel S Shaw, Misaki N Natsuaki, Helen L Egger, Jenae M Neiderhiser

Open access · hybridAbstract read
In one paragraph

Article in Developmental psychology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Integrating the family stress model within a longitudinal sibling-adoption study of adolescent externalizing behavior.Journal of research on adolescence : the official journal of the Society for Research on Adolescence · 2025
    Article
  7. Article
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  11. Article
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  14. Parenting in the Context of the Child: Genetic and Social Processes.Monographs of the Society for Research in Child Development · 2022
    Article
  15. Article
  16. Article
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  18. Article
  19. Disruptive Behavior in Siblings Discordant for Exposure to Maternal Smoking During Pregnancy: A Multi-rater Approach.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2020
    Article
  20. The Early Growth and Development Study: A Dual-Family Adoption Study from Birth Through Adolescence.Twin research and human genetics : the official journal of the International Society for Twin Studies · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Kristine MarceauDepartment of Human Development and Family Studies.ORCID 0000-0002-8924-6597
Emily RolanDepartment of Human Development and Family Studies.
Leslie D LevePrevention Science Institute.
Jody M GanibanDepartment of Psychology.
David ReissChild Study Center.
Daniel S ShawDepartment of Psychology.
Misaki N NatsuakiDepartment of Psychology.
Helen L EggerChild Study Center.ORCID 0000-0001-8447-5350
Jenae M NeiderhiserDepartment of Psychology.
Child Development Center · QAPrevention Institute · US

Funding

The Early Growth and Development Study Pediatric CohortUH3OD023389 · OD · UNIVERSITY OF OREGON · PI Jody M. Ganiban, Leslie Diane Leve · 2018 to 2026
$16.6M
The Early Growth and Development Study: Family Process, Genes and School EntryR01HD042608 · NICHD · OREGON SOCIAL LEARNING CENTER, INC. · PI CAPALDI, DEBORAH M. · 2002 to 2011
$14.9M
The Early Growth and Development Study Pediatric CohortUG3OD023389 · OD · UNIVERSITY OF OREGON · PI GANIBAN, JODY M., LEVE, LESLIE DIANE · 2016 to 2024
$7.5M
Genes, Prenatal Drug Exposure, and the Postnatal Environment: An Adoption StudyR01DA020585 · NIDA · PENNSYLVANIA STATE UNIVERSITY, THE · PI NEIDERHISER, JENAE M. · 2007 to 2011
$5.9M
An adoption study of the development of early substance use: the joint roles of genetic influences, prenatal risk, rearing environment, and pubertal maturationR01DA045108 · NIDA · PENNSYLVANIA STATE UNIVERSITY, THE · PI NEIDERHISER, JENAE M. · 2018 to 2022
$3.7M
Gene-Environment Interplay and Development of Psychiatric Symptoms in ChildrenR01MH092118 · NIMH · PENNSYLVANIA STATE UNIVERSITY, THE · PI LEVE, LESLIE DIANE, NEIDERHISER, JENAE M. · 2010 to 2014
$3.1M
Gene-Environment interplay and childhood obesity: An Adoption study.R01DK090264 · NIDDK · GEORGE WASHINGTON UNIVERSITY · PI GANIBAN, JODY M. · 2011 to 2015
$2.8M
Bio-behavioral Developmental Origins of Adolescent Substance AbuseK01DA039288 · NIDA · PURDUE UNIVERSITY · PI MARCEAU, KRISTINE · 2016 to 2020
$876k
Eunice Kennedy Shriver National Institute of Child Health and Human DevelopmentNational Institute on Drug AbuseNICHD NIH HHS R01 HD042608NIDA NIH HHS K01 DA039288NIDA NIH HHS R01 DA020585NIDA NIH HHS R01 DA045108NIDDK NIH HHS R01 DK090264NIH HHS UG3 OD023389NIH HHS UH3 OD023389NIMH NIH HHS R01 MH092118Office of the DirectorU.S. Public Health Service, National Institutes of Health; National Institute of Mental HealthU.S. Public Health Service, National Institutes of Health; National Institute on Drug Abuse; National Institute of Mental Health and OBSSRU.S. Public Health Services, National Institutes of Health; National Institute on Drug Abuse
6 · The paper itself

Abstract

This study examines interactions of heritable influences, prenatal substance use, and postnatal parental warmth and hostility on the development of conduct problems in middle childhood for boys and girls. Participants are 561 linked families, collected in 2 cohorts, including birth parents, adoptive parents, and adopted children. Heritable influences on internalizing and externalizing (including substance use) problems were derived from birth mothers' and fathers' symptoms, diagnoses, and age of onset from diagnostic interviews, and the proportion of first-degree relatives with the same type of problems. Smoking during pregnancy (SDP) and alcohol use during pregnancy were assessed retrospectively from birth mothers at 5 months postpartum. Earlier externalizing problems and parental warmth and hostility and were assessed at 1 assessment prior to the outcome (Cohort II: 4.5 years; Cohort I: 7 years). Conduct problems were symptoms from a diagnostic interview assessed at age 6 (Cohort II) or 8 (Cohort I). Findings from regression analyses suggest that (a) SDP plays an important role for the development of conduct problems, (b) some relatively well-accepted effects (e.g., parental hostility) were less important when simultaneously considering multiple factors influencing the development of conduct problems, and (c) main effects of genetic risk and SDP, and interactions among genetic risk and postnatal warmth, SDP and postnatal warmth, and genetic risk, SDP, and postnatal hostility for conduct problems were important for boys' but not girls' conduct problems. Replication is needed, but the current results provide preliminary but empirically grounded hypotheses for future research testing complex developmental models of conduct problems. (PsycINFO Database Record (c) 2019 APA, all rights reserved).

Indexed as

Parent-Child RelationsAlcoholismChildChild, PreschoolCohort StudiesConduct DisorderFemaleHostilityHumansMaleParentingPregnancyPrenatal Exposure Delayed EffectsRisk Factors

Identifiers

PMID30843708
PMCPMC6533149
OpenAlexW2921252916

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.