Evidence map›Paper›PMID 30843655›Full record

ArticleCongenital heart disease2019

Echocardiographic parameters of severe pulmonary regurgitation after surgical repair of tetralogy of Fallot.

An Van Berendoncks, Roderick Van Grootel, Jackie McGhie, Matthijs van Kranenburg, Myrthe Menting, Judith A A E Cuypers, Ad J J C Bogers, Maarten Witsenburg, Jolien W Roos-Hesselink, Annemien E van den Bosch

Abstract readComparative Study
In one paragraph

Article in Congenital heart disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

An Van BerendoncksDepartment of Cardiology, Erasmus Medical Center, Rotterdam, The Netherlands.
Roderick Van GrootelDepartment of Cardiology, Erasmus Medical Center, Rotterdam, The Netherlands.
Jackie McGhieDepartment of Cardiology, Erasmus Medical Center, Rotterdam, The Netherlands.
Matthijs van KranenburgDepartment of Cardiology, Erasmus Medical Center, Rotterdam, The Netherlands.
Myrthe MentingDepartment of Cardiology, Erasmus Medical Center, Rotterdam, The Netherlands.
Judith A A E CuypersDepartment of Cardiology, Erasmus Medical Center, Rotterdam, The Netherlands.
Ad J J C BogersDepartment of Cardiothoracic Surgery, Erasmus Medical Center, Rotterdam, The Netherlands.ORCID https://orcid.org/0000-0001-6200-1998
Maarten WitsenburgDepartment of Cardiology, Erasmus Medical Center, Rotterdam, The Netherlands.
Jolien W Roos-HesselinkDepartment of Cardiology, Erasmus Medical Center, Rotterdam, The Netherlands.ORCID https://orcid.org/0000-0002-6770-3830
Annemien E van den BoschDepartment of Cardiology, Erasmus Medical Center, Rotterdam, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsReliable evaluation of the severity and consequences of pulmonary regurgitation (PR) in patients with repaired tetralogy of Fallot (TOF) is crucial to timely identify the need for pulmonary valve intervention. We aimed to identify the accuracy of echocardiographic parameters to differentiate between moderate and severe PR, using phase contrast cardiac magnetic resonance imaging (CMR) as gold standard. METHODS AND

resultsIn this cross-sectional study, 45 TOF patients with both echocardiographic and CMR measurements of PR were enrolled. All quantitative and semiquantitative echocardiographic measurements such as pressure half time (PHT), Color flow jet width (CFJW), ratio CFJW/right ventricle outflow tract (RVOT) diameter, PR index and the presence of early termination of the PR jet, end-diastolic antegrade flow and diastolic backflow in main pulmonary artery (MPA), and PA branches correlated significantly with PR fraction on CMR. Qualitative assessment with color flow on echocardiography overestimated PR Multivariate linear regression analysis identified the ratio of CFJW/RVOT diameter and PHT as independent predictors of PR fraction. Accuracy of echo parameters was tested to differentiate between mild-to-moderate and severe PR Combining different echocardiographic parameters increased sensitivity and specificity. The addition of diastolic flow reversal in the PA branches to PHT below 167 milliseconds increased the NPV from 87% to 89% and PPV from 62% to 76%.

conclusionsComparison with CMR confirms that echocardiographic parameters are reliable in predicting PR severity. Combined measurement of diastolic flow reversal in the pulmonary artery branches and PHT is reliable in the detection of severe PR in the follow-up of TOF patients.

Indexed as

Postoperative ComplicationsAdolescentAdultCardiac Surgical ProceduresCross-Sectional StudiesEchocardiography, Doppler, ColorFemaleFollow-Up StudiesHeart VentriclesHumansMagnetic Resonance Imaging, CineMaleMiddle AgedPulmonary ValvePulmonary Valve InsufficiencyRetrospective StudiesCMRechocardiographypulmonary regurgitationTOF

Identifiers

PMID30843655
PMCPMC6849708

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.