Evidence map›Paper›PMID 30843638›Full record

ArticleTropical medicine & international health : TM & IH2019

A population-based study of the prevalence and risk factors of low-grade Plasmodium falciparum malaria infection in children aged 0-15 years old in northern Tanzania.

S Peprah, H Dhudha, H Ally, N Masalu, E Kawira, C N Chao, I O Genga, M Mumia, P A Were, T Kinyera and 7 more

Open access · bronzeAbstract read
In one paragraph

Article in Tropical medicine & international health : TM & IH, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research · 2023
    Article
  3. Burkitt lymphoma risk shows geographic and temporal associations withProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 4 countries.

S PeprahDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA.
H DhudhaEpidemiology of Burkitt Lymphoma in East African Children and Minors (EMBLEM) Study, Bugando Medical Center, Mwanza, Tanzania.
H AllyEpidemiology of Burkitt Lymphoma in East African Children and Minors (EMBLEM) Study, Bugando Medical Center, Mwanza, Tanzania.
N MasaluEpidemiology of Burkitt Lymphoma in East African Children and Minors (EMBLEM) Study, Bugando Medical Center, Mwanza, Tanzania.
E KawiraEMBLEM Study, Shirati Health and Educational Foundation, Shirati, Tanzania.
C N ChaoEpidemiology of Burkitt Lymphoma in East African Children and Minors (EMBLEM) Study, Bugando Medical Center, Mwanza, Tanzania.
I O GengaEMBLEM Study, Academic Model Providing Access to Healthcare, Eldoret, Kenya.
M MumiaEMBLEM Study, Academic Model Providing Access to Healthcare, Eldoret, Kenya.
P A WereEMBLEM Study, Academic Model Providing Access to Healthcare, Eldoret, Kenya.
T KinyeraEMBLEM Study, African Field Epidemiology Network, Kampala, Uganda.
I OtimEMBLEM Study, African Field Epidemiology Network, Kampala, Uganda.
I D LegasonEMBLEM Study, African Field Epidemiology Network, Kampala, Uganda.
R J BiggarDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA.
K BhatiaDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA.
J J GoedertDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA.
R M PfeifferDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA.
S M MbulaiteyeDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA.
Bugando Medical Centre · TZAfrican Field Epidemiology Network · UGAMPATH · KEDivision of Cancer Epidemiology and GeneticsNational Cancer Institute · US

Funding

Epidemiology and Natural History of Cancer-Associated VirusesZIACP010176 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI MBULAITEYE, SAM M · 2009 to 2025
$33.7M
Infections, immunity, and inflammation in cancerZ01CP010150 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI ENGELS, ERIC A · 2000 to 2008
$3.0M
Intramural NIH HHS Z01 CP010150
6 · The paper itself

Abstract

objectivesNorthern Tanzania experiences significant malaria-related morbidity and mortality, but accurate data are scarce. We update the data on patterns of low-grade Plasmodium falciparum malaria infection among children in northern Tanzania.

methodsPlasmodium falciparum malaria prevalence (pfPR) was assessed in a representative sample of 819 children enrolled in 94 villages in northern Tanzania between October 2015 and August 2016, using a complex survey design. Individual- and household-level risk factors for pfPR were elicited using structured questionnaires. pfPR was assessed using rapid diagnostic tests (RDTs) and thick film microscopy (TFM). Associations with pfPR, based on RDT, were assessed using adjusted odds ratios (aOR) and confidence intervals (CI) from weighted survey logistic regression models.

resultsPlasmodium falciparum malaria prevalence (pfPR) was 39.5% (95% CI: 31.5, 47.5) by RDT and 33.4% (26.0, 40.6) by TFM. pfPR by RDT was inversely associated with higher-education parents, especially mothers (5-7 years of education: aOR 0.55; 95% CI: 0.31, 0.96, senior secondary education: aOR 0.10; 95% CI: 0.02, 0.55), living in a house near the main road (aOR 0.34; 95% CI: 0.15, 0.76), in a larger household (two rooms: aOR 0.40; 95% CI: 0.21, 0.79, more than two rooms OR 0.35; 95% CI: 0.20, 0.62). Keeping a dog near or inside the house was positively associated with pfPR (aOR 2.01; 95% CI: 1.26, 3.21). pfPR was not associated with bed-net use or indoor residual spraying.

conclusionsNearly 40% of children in northern Tanzania had low-grade malaria antigenaemia. Higher parental education and household metrics but not mosquito bed-net use were inversely associated with pfPR.

Indexed as

Plasmodium falciparumAdolescentAnimalsAntigensChildChild, PreschoolCross-Sectional StudiesDogsEducational StatusFamily CharacteristicsFemaleHousingHumansInfantInfant, NewbornLogistic ModelsAntigensAfricaAfriqueBurkitt lymphomaépidémiologieepidemiologylymphome de Burkittlymphome non hodgkinienmalariaMalarianon-Hodgkin lymphomapaludismePlasmodium falciparumTanzaniaTanzanie

Identifiers

PMID30843638
PMCPMC6499672
OpenAlexW2922297192

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.