Evidence map›Paper›PMID 30842987›Full record

ArticleACS omega2019

A FRET-Based Fluorogenic Trehalose Dimycolate Analogue for Probing Mycomembrane-Remodeling Enzymes of Mycobacteria.

Nathan J Holmes, Herbert W Kavunja, Yong Yang, B Dillon Vannest, Claudia N Ramsey, Dana M Gepford, Nicholas Banahene, Anne W Poston, Brent F Piligian, Donald R Ronning and 2 more

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 32 citations in OpenAlex.

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  11. A versatile fluorescence-quenched substrate for quantitative measurement of glucocerebrosidase activity within live cells.Proceedings of the National Academy of Sciences of the United States of America · 2022
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  17. Microbiology spectrum · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Nathan J HolmesDepartment of Chemistry and Biochemistry, Central Michigan University, Mount Pleasant, Michigan 48859, United States.
Herbert W KavunjaDepartment of Chemistry and Biochemistry, Central Michigan University, Mount Pleasant, Michigan 48859, United States.
Yong YangDivision of Genetics, Wadsworth Center, New York State Department of Health, Albany, New York 12208, United States.
B Dillon VannestDepartment of Chemistry and Biochemistry, Central Michigan University, Mount Pleasant, Michigan 48859, United States.
Claudia N RamseyDepartment of Chemistry and Biochemistry, Central Michigan University, Mount Pleasant, Michigan 48859, United States.
Dana M GepfordDepartment of Chemistry and Biochemistry, Central Michigan University, Mount Pleasant, Michigan 48859, United States.
Nicholas BanaheneDepartment of Chemistry and Biochemistry, Central Michigan University, Mount Pleasant, Michigan 48859, United States.
Anne W PostonDepartment of Chemistry and Biochemistry, Central Michigan University, Mount Pleasant, Michigan 48859, United States.
Brent F PiligianDepartment of Chemistry and Biochemistry, Central Michigan University, Mount Pleasant, Michigan 48859, United States.
Donald R RonningDepartment of Chemistry and Biochemistry, University of Toledo, Toledo, Ohio 43606-3390, United States.
Anil K OjhaDivision of Genetics, Wadsworth Center, New York State Department of Health, Albany, New York 12208, United States.
Benjamin M SwartsDepartment of Chemistry and Biochemistry, Central Michigan University, Mount Pleasant, Michigan 48859, United States.
Central Michigan University · USNew York State Department of Health · USUniversity of Toledo · US

Funding

Alternative Ribosomes & Antibiotic Tolerance in MycobacteriaR01AI132422 · NIAID · WADSWORTH CENTER · PI RAJENDRA K AGRAWAL, Anil Kumar Ojha · 2017 to 2026
$3.8M
Understanding trehalose synthesis and utilization in mycobacteriaR01AI105084 · NIAID · UNIVERSITY OF TOLEDO · PI RONNING, DONALD R, SUCHECK, STEVEN · 2013 to 2022
$3.7M
Physiology of Mycobacterium Tuberculosis with Hibernating RibosomesR21AI144474 · NIAID · WADSWORTH CENTER · PI OJHA, ANIL KUMAR · 2019 to 2020
$466k
NIAID NIH HHS R01 AI105084NIAID NIH HHS R01 AI132422
6 · The paper itself

Abstract

The mycobacterial outer membrane, or mycomembrane, is essential for the viability and virulence of

Identifiers

PMID30842987
PMCPMC6396954
OpenAlexW2917639779

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.