Evidence map›Paper›PMID 30842963›Full record

ArticleWorld journal of clinical cases2019

Hydrochloric acid enhanced radiofrequency ablation for treatment of large hepatocellular carcinoma in the caudate lobe: Report of three cases.

Han-Xia Deng, Jin-Hua Huang, Wan Yee Lau, Fei Ai, Min-Shan Chen, Zhi-Mei Huang, Tian-Qi Zhang, Meng-Xuan Zuo

Open access · diamondAbstract readCase Reports
In one paragraph

Article in World journal of clinical cases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Han-Xia DengDepartment of Minimally Invasive Interventional Therapy, Cancer Centre of Sun Yat-sen University, Guangzhou 510060, Guangdong Province, China.
Jin-Hua HuangDepartment of Minimally Invasive Interventional Therapy, Cancer Centre of Sun Yat-sen University, Guangzhou 510060, Guangdong Province, China.
Wan Yee LauDepartment of Hepatobiliary Surgery, Cancer Centre of Sun Yat-sen University, Guangzhou 510060, Guangdong Province, China.
Fei AiDepartment of Minimally Invasive Interventional Therapy, Cancer Centre of Sun Yat-sen University, Guangzhou 510060, Guangdong Province, China.
Min-Shan ChenDepartment of Hepatobiliary Surgery, Cancer Centre of Sun Yat-sen University, Guangzhou 510060, Guangdong Province, China.
Zhi-Mei HuangDepartment of Minimally Invasive Interventional Therapy, Cancer Centre of Sun Yat-sen University, Guangzhou 510060, Guangdong Province, China.
Tian-Qi ZhangDepartment of Minimally Invasive Interventional Therapy, Cancer Centre of Sun Yat-sen University, Guangzhou 510060, Guangdong Province, China.
Meng-Xuan ZuoDepartment of Minimally Invasive Interventional Therapy, Cancer Centre of Sun Yat-sen University, Guangzhou 510060, Guangdong Province, China.
Sun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo report on the use of percutaneous hydrochloric acid (HCl) enhanced radiofrequency ablation (HRFA) for the treatment of large (maximum diameter ≥ 5 cm) hepatocellular carcinoma (HCC) in the caudate lobe. CASE SUMMARY: Between August 2013 and June 2016, three patients with a large HCC (maximum diameter: 5.0, 5.7, and 8.1 cm) in the caudate lobe were treated by transarterial chemoembolization followed by computer tomography (CT) guided RFA using a monopolar perfusion RF electrode, which was enhanced by local infusion of 10% HCl at 0.2 mL/min (total volume, 3 to 12 mL). The output power of HRFA reached 100 W, and the average ablation time was 39 min (range, 15 to 60 min). Two patients each underwent one session of HRFA and one patient two sessions. After treatment, CT/magnetic resonance imaging showed that all the three lesions were completely ablated. There was no major complication. Two patients had asymptomatic bile duct dilatation. One patient died of tongue cancer 24 mo after ablation. The remaining two patients were alive and no area of enhancement is detected in the caudate lobe at 28 and 60 mo after ablation, respectively.

conclusionPercutaneous CT-guided HRFA is safe and efficacious in treating large HCC in the caudate lobe.

Indexed as

Case reportCaudate lobeHydrochloric acidHydrochloric acid enhanced radiofrequency ablationLarge hepatocellular carcinomaRadiofrequency ablation

Identifiers

PMID30842963
PMCPMC6397810
OpenAlexW2916581966

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.