Evidence map›Paper›PMID 30842799›Full record

ArticleJournal of dentistry (Tehran, Iran)2018

Evaluation of the Effect of MTAD on Expression of Enterococcus faecalis Virulence Factors Considering the Role of Different Obturating Materials.

Behnam Bolhari, Abbas Bahador, Mehrfam Khoshkhounejad, Mahsa Sobhi Afshar, Mohammad Moghaddaszadeh

Open access · diamondAbstract read
PubMed Full text at PMC
In one paragraph

Article in Journal of dentistry (Tehran, Iran), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Behnam BolhariAssociate Professor, Department of Endodontics, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran; Laser Research Center in Dentistry, Tehran University of Medical Sciences, Tehran, Iran.
Abbas BahadorAssociate Professor, Department of Microbiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Mehrfam KhoshkhounejadAssistant Professor, Department of Endodontics, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.
Mahsa Sobhi AfsharAssistant Professor, Department of Endodontics, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.
Mohammad MoghaddaszadehPrivate Practice, Tehran, Iran.
Tehran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe aim of this study was to determine the effect of MTAD on the expression of virulence factors of Enterococcus faecalis (E.faecalis) considering the role of Guttapercha/AH26 or Resilon/RealSeal SE as root canal obturating materials. MATERIALS AND

methodsOne-hundred and forty-four single-rooted human teeth were instrumented to a standardized apical size. Root canals were infected by E.faecalis (ATCC 29212). Ninety teeth were irrigated with MTAD and randomly divided into three groups. In two groups, root canals were obturated by either Gutta-percha/AH26 or Resilon/RealSeal SE. Root canals were kept unobturated in the third group. The remaining 54 teeth received no final irrigation. All groups were then subdivided into three timepoint subgroups in which dentin powder was obtained from each sample to determine the expression of specific virulence factors of E.faecalis (

resultsMTAD was effective against the expression of most of the tested virulence factors, and Gutta-percha/AH26 increased the antibacterial efficacy of MTAD.

conclusionsMTAD could inhibit the expression of some known virulence factors of E.faecalis at the majority of tested timepoints. This may partly explain some of the mechanisms of antimicrobial efficacy of MTAD against this resistant microorganism which is known as one of the main causes of failure of root canal treatment.

Indexed as

Enterococcus faecalisGutta-PerchaMTADResilon SealerVirulence Factors

Identifiers

PMID30842799
PMCPMC6399463
OpenAlexW2906680931

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.