ArticleFrontiers in neurology2019
Cortico-Muscular Coherence Is Reduced Acutely Post-stroke and Increases Bilaterally During Motor Recovery: A Pilot Study.
Article in Frontiers in neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
41 citing papers in PubMed, 1 synthesis or guideline pooled it, 78 citations in OpenAlex.
- Combined Use of EMG and EEG Techniques for Neuromotor Assessment in Rehabilitative Applications: A Systematic Review.Sensors (Basel, Switzerland) · 2021Pooled it
- Tai Ji for stroke rehabilitation: a randomized controlled trial on improving upper limb function and cortico-muscular coupling in stroke patients.Journal of neuroengineering and rehabilitation · 2026Trial
- Corticomuscular Coherence in Post-Stroke Motor Function and Recovery.Brain sciences · 2026Article
- Paretic Hand Beta Band Intermuscular Coherence Increases Following non-Paretic Hand Exercise to Task-Failure in Chronic Stroke.Restorative neurology and neuroscience · 2026Article
- Corticomuscular coherence and its non-invasive modulation in stroke applications: a narrative review.Neuroimage. Reports · 2026Article
- Decoding multi-class motor attempt from the affected unilateral limbs in chronic stroke patients.Journal of neuroengineering and rehabilitation · 2026Article
- Prefrontal Hierarchical Control of Corticomuscular Coherence in Stroke.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2026Article
- Corticomuscular coupling alterations in subacute stroke patients: insights from fNIRS and sEMG.BMC neurology · 2025Article
- Corticomuscular coupling study for post-stroke rehabilitation: a scoping review.Journal of neuroengineering and rehabilitation · 2025Article
- Uncovering attempted movements of the paralyzed upper limb after stroke through EEG and EMG.Journal of neuroengineering and rehabilitation · 2025Article
- Neuromechanical Predictors of Clinical Scores of Balance and Functional Mobility in Chronic Stroke Survivors - A Machine Learning Approach.medRxiv : the preprint server for health sciences · 2025Article
- Electrophysiological Approaches to Understanding Brain-Muscle Interactions During Gait: A Systematic Review.Bioengineering (Basel, Switzerland) · 2025Review
- Reduced beta bursting underpins loss of corticomuscular coherence in amyotrophic lateral sclerosis.Brain communications · 2025Article
- Neural control meets biomechanics in the motor assessment of neurological disorders: a narrative review.Frontiers in neural circuits · 2025Review
- Associations between structural injury and task-based corticomuscular connectivity after stroke.Frontiers in neurology · 2025Article
- Case report: Exploring cortico-muscular coherence during Mirror visual feedback for deafferentation pain: a proof-of-concept study.Frontiers in human neuroscience · 2025Article
- Context-dependent reduction in corticomuscular coupling for balance control in chronic stroke survivors.Experimental brain research · 2024Article
- Hebbian plasticity induced by temporally coincident BCI enhances post-stroke motor recovery.Scientific reports · 2024Article
- Cortico-muscular coherence of time-frequency and spatial characteristics under movement observation, movement execution, and movement imagery.Cognitive neurodynamics · 2024Article
- The neuromechanical of Beta-band corticomuscular coupling within the human motor system.Frontiers in neuroscience · 2024Review
Corrections and comments
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Authors and funding
13 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Motor recovery following stroke is believed to necessitate alteration in functional connectivity between cortex and muscle. Cortico-muscular coherence has been proposed as a potential biomarker for post-stroke motor deficits, enabling a quantification of recovery, as well as potentially indicating the regions of cortex involved in recovery of function. We recorded simultaneous EEG and EMG during wrist extension from healthy participants and patients following ischaemic stroke, evaluating function at three time points post-stroke. EEG-EMG coherence increased over time, as wrist mobility recovered clinically, and by the final evaluation, coherence was higher in the patient group than in the healthy controls. Moreover, the cortical distribution differed between the groups, with coherence involving larger and more bilaterally scattered areas of cortex in the patients than in the healthy participants. The findings suggest that EEG-EMG coherence has the potential to serve as a biomarker for motor recovery and to provide information about the cortical regions that should be targeted in rehabilitation therapies based on real-time EEG.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.