Evidence map›Paper›PMID 30842713›Full record

ArticleInternational journal of health sciences

Possible inflammatory responses in hypercholesterolemia patients receiving treatment using raw liquid extract of young cashew leaves in herbal homes in Nigeria.

Mathew Folaranmi Olaniyan, Donatus F N Ozuruoke, Temitayo Afolabi

Open access · greenAbstract read
In one paragraph

Article in International journal of health sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Mathew Folaranmi OlaniyanDepartment of Medical Laboratory Science, Edo University, Iyamho-Nigeria.
Donatus F N OzuruokeDepartment, Medical Laboratory Science Council of Nigeria, Abuja.
Temitayo AfolabiDepartment of Medical Laboratory Science, Achievers University, Owo-Nigeria.
Achievers University · NGMedical Laboratory Science Council of Nigeria · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe objective of this study was to determine the possible inflammatory responses in hypercholesterolemia patients receiving treatment using raw liquid extract of young cashew leaves in some herbal homes in Nigeria.

methodsHypercholesterolemia patients (27: Aged 31-53 years; female - 10 and male - 17) 20 herbal homes in Saki-West, Saki-East, and ATISBO local governments constituting a Federal constituency in Nigeria, and non-hypercholesterolemia apparently healthy participants (50: Aged 20-64 years; female - 25 and male - 25) were recruited from the same federal constituency as test and control subjects, respectively. About 60 ml of this extract were given to the patients for an average of 14 days when there was a significant decrease in their plasma cholesterol. Plasma cholesterol was determined in the subjects using COBAS C111 auto chemistry analyzer; plasma tumor necrosis factor-alpha (TNF-α), interleukin (IL)-6, 8, and 29, intrahepatic chemokines such as fibrinogen and C-reactive protein (CRP), IL-6, CRP, hepatitis B surface antigen, anti-hepatitis C virus, and anti-human immunodeficiency virus were immunochemically determined by enzyme-linked immunosorbent assay, and identification of

resultsThere was a significant reduction in the plasma values of cholesterol, TNF-α, IL-6, and CRP with a significant increase in plasma aspartate transaminase (AST) and alanine transaminase (ALT). In the hypercholesterolemia patients who were supplemented with raw liquid extract of young cashew leaves compared with the control and their basal samples ( DISCUSSION: Supplementation of raw liquid extract of young cashew leaves can cause a significant reduction in the plasma values of cholesterol TNF-α, IL-6, and CRP with an increase in plasma AST and ALT. In the hypercholesterolemia patients due to the phytochemicals in young cashew leaves.

Indexed as

Herbal homesherbal treatmenthypercholesterolemia patientsinflammatory responsesNigeriayoung cashew leaves

Identifiers

PMID30842713
PMCPMC6392480
OpenAlexW2907616259

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.