Evidence map›Paper›PMID 30842418›Full record

ArticleNature communications2019

Neutrophils promote the development of reparative macrophages mediated by ROS to orchestrate liver repair.

Wenting Yang, Yuandong Tao, Yan Wu, Xinyuan Zhao, Weijie Ye, Dianyuan Zhao, Ling Fu, Caiping Tian, Jing Yang, Fuchu He and 1 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 230 papers.

0numbers the graph read from it
0cells of the map it votes in
230citing papers in PubMed
15.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

230 citing papers in PubMed, 357 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Neutrophil depletion exacerbatesFood and waterborne parasitology · 2026
    Article
  7. CD177Gut · 2026
    Article
  8. Review
  9. HypervirulentMicrobiology spectrum · 2026
    Article
  10. Article
  11. Systemic and metabolic control of liver regeneration.Trends in endocrinology and metabolism: TEM · 2026
    Review
  12. PAF Triggered Pyroptotic NETosis Aggravates Myocardial Ischemia/Reperfusion Injury.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  13. Article
  14. EREG-secreting THBS1Hepatobiliary surgery and nutrition · 2026
    Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article

170 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Wenting YangState Key Laboratory of Proteomics, National Center for Protein Sciences, Beijing. Beijing Proteome Research Center, Beijing Institute of Lifeomics, 102206, Beijing, China.
Yuandong TaoState Key Laboratory of Proteomics, National Center for Protein Sciences, Beijing. Beijing Proteome Research Center, Beijing Institute of Lifeomics, 102206, Beijing, China.
Yan WuState Key Laboratory of Proteomics, National Center for Protein Sciences, Beijing. Beijing Proteome Research Center, Beijing Institute of Lifeomics, 102206, Beijing, China.
Xinyuan ZhaoState Key Laboratory of Proteomics, National Center for Protein Sciences, Beijing. Beijing Proteome Research Center, Beijing Institute of Lifeomics, 102206, Beijing, China.
Weijie YeState Key Laboratory of Proteomics, National Center for Protein Sciences, Beijing. Beijing Proteome Research Center, Beijing Institute of Lifeomics, 102206, Beijing, China.
Dianyuan ZhaoState Key Laboratory of Proteomics, National Center for Protein Sciences, Beijing. Beijing Proteome Research Center, Beijing Institute of Lifeomics, 102206, Beijing, China.
Ling FuState Key Laboratory of Proteomics, National Center for Protein Sciences, Beijing. Beijing Proteome Research Center, Beijing Institute of Lifeomics, 102206, Beijing, China.
Caiping TianState Key Laboratory of Proteomics, National Center for Protein Sciences, Beijing. Beijing Proteome Research Center, Beijing Institute of Lifeomics, 102206, Beijing, China.
Jing YangState Key Laboratory of Proteomics, National Center for Protein Sciences, Beijing. Beijing Proteome Research Center, Beijing Institute of Lifeomics, 102206, Beijing, China.ORCID http://orcid.org/0000-0001-8486-273X
Fuchu HeState Key Laboratory of Proteomics, National Center for Protein Sciences, Beijing. Beijing Proteome Research Center, Beijing Institute of Lifeomics, 102206, Beijing, China. hefc@nic.bmi.ac.cn.
Li TangState Key Laboratory of Proteomics, National Center for Protein Sciences, Beijing. Beijing Proteome Research Center, Beijing Institute of Lifeomics, 102206, Beijing, China. tangli08@aliyun.com.
Beijing Proteome Research Center · CNAnhui Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phagocytes, including neutrophils and macrophages, have been suggested to function in a cooperative way in the initial phase of inflammatory responses, but their interaction and integration in the resolution of inflammation and tissue repair remain unclear. Here we show that neutrophils have crucial functions in liver repair by promoting the phenotypic conversion of pro-inflammatory Ly6C

Indexed as

AcetaminophenAdoptive TransferAnimalsBone Marrow TransplantationCells, CulturedChemical and Drug Induced Liver InjuryDisease Models, AnimalHumansLiverLiver RegenerationMacrophagesMaleMiceMice, KnockoutNADPH Oxidase 2NeutrophilsAcetaminophenCybb protein, mouseNADPH Oxidase 2Reactive Oxygen Species

Identifiers

PMID30842418
PMCPMC6403250
OpenAlexW2920290417

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.