Evidence map›Paper›PMID 30842328›Full record

ArticleJournal of virology2019

SUMO1 Modification Facilitates Avibirnavirus Replication by Stabilizing Polymerase VP1.

Huansheng Wu, Hui Yang, Gang Ji, Tuyuan Zheng, Yina Zhang, Tingjuan Deng, Xiaojuan Zheng, Jiyong Zhou, Boli Hu

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 23 citations in OpenAlex.

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  6. Protein arginine methylation in viral infection and antiviral immunity.International journal of biological sciences · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Huansheng Wu *MOA Key Laboratory of Animal Virology, Department of Veterinary Medicine, Zhejiang University, Hangzhou, China.
Hui Yang *MOA Key Laboratory of Animal Virology, Department of Veterinary Medicine, Zhejiang University, Hangzhou, China.
Gang JiInstitute of Immunology, Nanjing Agricultural University, Nanjing, China.
Tuyuan ZhengInstitute of Immunology, Nanjing Agricultural University, Nanjing, China.
Yina ZhangMOA Key Laboratory of Animal Virology, Department of Veterinary Medicine, Zhejiang University, Hangzhou, China.
Tingjuan DengMOA Key Laboratory of Animal Virology, Department of Veterinary Medicine, Zhejiang University, Hangzhou, China.
Xiaojuan ZhengMOA Key Laboratory of Animal Virology, Department of Veterinary Medicine, Zhejiang University, Hangzhou, China.
Jiyong ZhouMOA Key Laboratory of Animal Virology, Department of Veterinary Medicine, Zhejiang University, Hangzhou, China jyzhou@zju.edu.cn bolihu28@126.com.
Boli HuMOA Key Laboratory of Animal Virology, Department of Veterinary Medicine, Zhejiang University, Hangzhou, China jyzhou@zju.edu.cn bolihu28@126.com.
Zhejiang University · CNNanjing Agricultural University · CNFirst Affiliated Hospital Zhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

SUMOylation is a posttranslational modification that has crucial roles in diverse cellular biological pathways and in various viral life cycles. In this study, we found that the VP1 protein, the RNA-dependent RNA polymerase of avibirnavirus infectious bursal disease virus (IBDV), regulates virus replication by SUMOylation during infection. Our data demonstrated that the polymerase VP1 is efficiently modified by small ubiquitin-like modifier 1 (SUMO1) in avibirnavirus-infected cell lines. Mutation analysis showed that residues

Indexed as

AvibirnavirusHEK293 CellsHost-Pathogen InteractionsHumansInfectious bursal disease virusProtein Processing, Post-TranslationalRNA-Dependent RNA PolymeraseSUMO-1 ProteinSumoylationUbiquitinationViral ProteinsViral Structural ProteinsVirus ReplicationRNA-Dependent RNA PolymeraseSUMO-1 ProteinSUMO1 protein, humanViral ProteinsViral Structural ProteinsVP1 protein, infectious bursal disease virusavibirnavirusstabilitySUMO1 modificationviral replicationVP1 protein

Identifiers

PMID30842328
PMCPMC6498067
OpenAlexW2921650845

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.