Evidence map›Paper›PMID 30842322›Full record

ArticleJournal of virology2019

A Highly Unusual V1 Region of Env in an Elite Controller of HIV Infection.

Zachary A Silver, Gordon M Dickinson, Michael S Seaman, Ronald C Desrosiers

Abstract read
In one paragraph

Article in Journal of virology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Effects of Korean red ginseng on the HIV-1Journal of ginseng research · 2026
    Article
  2. Article
  3. Article
  4. HIV controllers: hope for a functional cure.Frontiers in immunology · 2025
    Review
  5. Article
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  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Zachary A SilverMedical Scientist Training Program, Miller School of Medicine, University of Miami, Miami, Florida, USA.
Gordon M DickinsonInfectious Diseases Section, Miami Veterans Affairs Health Care System, University of Miami, Miami, Florida, USA.
Michael S SeamanCenter for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.
Ronald C DesrosiersDepartment of Pathology, Miller School of Medicine, University of Miami, Miami, Florida, USA r.desrosiers@med.miami.edu.

Funding

Functional Role of O-Glycosylation of HIV-1R01AI104523 · NIAID · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI DESROSIERS, RONALD C · 2013 to 2024
$4.1M
Virologic determinants of HIV elite controlF30AI134381 · NIAID · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI SILVER, ZACHARY AARON · 2018 to 2020
$150k
NIAID NIH HHS F30 AI134381NIAID NIH HHS R01 AI104523
6 · The paper itself

Abstract

HIV elite controllers represent a remarkable minority of patients who maintain normal CD4

Indexed as

Amino Acid SequenceAntibodies, MonoclonalAntibodies, Neutralizingenv Gene Products, Human Immunodeficiency VirusEpitopesGlycosylationHIV-1HIV AntibodiesHIV Envelope Protein gp120HIV InfectionsHumansImmune EvasionNeutralization TestsPeptide FragmentsPolysaccharidesAntibodies, MonoclonalAntibodies, Neutralizingenv Gene Products, Human Immunodeficiency VirusEpitopesHIV AntibodiesHIV Envelope Protein gp120HIV envelope protein gp120 (135-148)Peptide FragmentsPolysaccharidesbNAbelite controllerHIV-1V1 domain

Identifiers

PMID30842322
PMCPMC6498048

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.