Evidence map›Paper›PMID 30842319›Full record

ArticleJournal of virology2019

Dehydrojuncusol, a Natural Phenanthrene Compound Extracted from

Marie-Emmanuelle Sahuc, Ramla Sahli, Céline Rivière, Véronique Pène, Muriel Lavie, Alexandre Vandeputte, Priscille Brodin, Arielle R Rosenberg, Jean Dubuisson, Riadh Ksouri and 3 more

Abstract read
In one paragraph

Article in Journal of virology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Discovery of Anti-Coronavirus Cinnamoyl Triterpenoids Isolated fromInternational journal of molecular sciences · 2023
    Article
  2. Article
  3. Article
  4. Luteolin Isolated fromMolecules (Basel, Switzerland) · 2023
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Marie-Emmanuelle Sahuc *Center for Infection and Immunity of Lille (CIIL), University of Lille, CNRS, INSERM, CHU Lille, Institut Pasteur de Lille, U1019, UMR 8204, Lille, France.
Ramla Sahli *Institut Charles Viollette (ICV), University of Lille, INRA, ISA, University Artois, Université du Littoral Côte d'Opale, EA 7394, Lille, France.
Céline RivièreInstitut Charles Viollette (ICV), University of Lille, INRA, ISA, University Artois, Université du Littoral Côte d'Opale, EA 7394, Lille, France.ORCID 0000-0002-8618-5530
Véronique PèneUniversity Paris Descartes, EA4474 "Hepatitis C Virology," Paris, France.
Muriel LavieCenter for Infection and Immunity of Lille (CIIL), University of Lille, CNRS, INSERM, CHU Lille, Institut Pasteur de Lille, U1019, UMR 8204, Lille, France.ORCID 0000-0003-3308-811X
Alexandre VandeputteCenter for Infection and Immunity of Lille (CIIL), University of Lille, CNRS, INSERM, CHU Lille, Institut Pasteur de Lille, U1019, UMR 8204, Lille, France.
Priscille BrodinCenter for Infection and Immunity of Lille (CIIL), University of Lille, CNRS, INSERM, CHU Lille, Institut Pasteur de Lille, U1019, UMR 8204, Lille, France.
Arielle R RosenbergUniversity Paris Descartes, EA4474 "Hepatitis C Virology," Paris, France.
Jean DubuissonCenter for Infection and Immunity of Lille (CIIL), University of Lille, CNRS, INSERM, CHU Lille, Institut Pasteur de Lille, U1019, UMR 8204, Lille, France.ORCID 0000-0003-1626-7693
Riadh KsouriLaboratory of Aromatic and Medicinal Plants, Biotechnology Centre of Borj-Cédria (CBBC), Hammam-lif, Tunisia.
Yves RouilléCenter for Infection and Immunity of Lille (CIIL), University of Lille, CNRS, INSERM, CHU Lille, Institut Pasteur de Lille, U1019, UMR 8204, Lille, France.ORCID 0000-0003-0788-9271
Sevser SahpazInstitut Charles Viollette (ICV), University of Lille, INRA, ISA, University Artois, Université du Littoral Côte d'Opale, EA 7394, Lille, France.
Karin SéronCenter for Infection and Immunity of Lille (CIIL), University of Lille, CNRS, INSERM, CHU Lille, Institut Pasteur de Lille, U1019, UMR 8204, Lille, France karin.seron@ibl.cnrs.fr.ORCID 0000-0002-9667-133X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent emergence of direct-acting antivirals (DAAs) targeting hepatitis C virus (HCV) proteins has considerably enhanced the success of antiviral therapy. However, the appearance of DAA-resistant-associated variants is a cause of treatment failure, and the high cost of DAAs renders the therapy not accessible in countries with inadequate medical infrastructures. Therefore, the search for new inhibitors with a lower cost of production should be pursued. In this context, the crude extract of

Indexed as

Antiviral AgentsCell LineDrug Resistance, ViralGenotypeHEK293 CellsHepacivirusHepatitis CHepatitis C, ChronicHepatocytesHumansPhenanthrenesPhenethylaminesPlant ExtractsProtease InhibitorsRepliconRhizomeAntiviral AgentsN,N-dimethylphenylethylaminephenanthrenePhenanthrenesPhenethylaminesPlant ExtractsProtease Inhibitorsantiviral agentsdehydrojuncusolhepatitis C virusnatural antimicrobial productsphenanthreneviral replication

Identifiers

PMID30842319
PMCPMC6498043

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.