Evidence map›Paper›PMID 30842286›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

Genome mining and biosynthesis of a polyketide from a biofertilizer fungus that can facilitate reductive iron assimilation in plant.

Mengbin Chen, Qikun Liu, Shu-Shan Gao, Abbegayle E Young, Steven E Jacobsen, Yi Tang

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.

  1. BioprospectingFrontiers in fungal biology · 2021
    Pooled it
  2. Isolation and characterization ofFrontiers in microbiology · 2026
    Article
  3. Article
  4. The endophytic fungusCurrent research in microbial sciences · 2025
    Article
  5. Journal of fungi (Basel, Switzerland) · 2024
    Article
  6. Article
  7. Review
  8. Use ofMicroorganisms · 2024
    Review
  9. Genomic Based Analysis of the Biocontrol SpeciesJournal of fungi (Basel, Switzerland) · 2023
    Article
  10. Article
  11. Article
  12. Review
  13. Strain improvement ofFrontiers in microbiology · 2023
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Mengbin ChenDepartment of Chemical and Biomolecular Engineering, University of California, Los Angeles, CA 90095.
Qikun LiuDepartment of Molecular Cell and Developmental Biology, University of California, Los Angeles, CA 90095.ORCID 0000-0003-2489-2907
Shu-Shan GaoDepartment of Chemical and Biomolecular Engineering, University of California, Los Angeles, CA 90095.
Abbegayle E YoungDepartment of Chemical and Biomolecular Engineering, University of California, Los Angeles, CA 90095.
Steven E JacobsenDepartment of Molecular Cell and Developmental Biology, University of California, Los Angeles, CA 90095.
Yi TangDepartment of Chemical and Biomolecular Engineering, University of California, Los Angeles, CA 90095; yitang@g.ucla.edu.ORCID 0000-0003-1597-0141
University of California, Los Angeles · USHoward Hughes Medical Institute · US

Funding

MIRA: Enzymology and Self-Resistance of Natural Product BiosynthesisR35GM118056 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Yi Tang · 2016 to 2026
$6.1M
NIGMS NIH HHS R35 GM118056
6 · The paper itself

Abstract

Fungi have the potential to produce a large repertoire of bioactive molecules, many of which can affect the growth and development of plants. Genomic survey of sequenced biofertilizer fungi showed many secondary metabolite gene clusters are anchored by iterative polyketide synthases (IPKSs), which are multidomain enzymes noted for generating diverse small molecules. Focusing on the biofertilizer

Indexed as

ArabidopsisIronMetabolic Networks and PathwaysMethylationMolecular ChaperonesMultigene FamilyPolyketidesPolyketide SynthasesTrichodermaIronMolecular ChaperonesPolyketidesPolyketide Synthasesbiofertilizerbiosynthesisiterative polyketide synthasenatural products

Identifiers

PMID30842286
PMCPMC6431147
OpenAlexW2921556980

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.