Evidence map›Paper›PMID 30842285›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

Parkinson's disease-linked

Xi Chen, Jennifer K Kordich, Erin T Williams, Nathan Levine, Allyson Cole-Strauss, Lee Marshall, Viviane Labrie, Jiyan Ma, Jack W Lipton, Darren J Moore

Erratum issuedOpen access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 73 papers.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed
12.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 122 citations in OpenAlex.

  1. Article
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  9. Review
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  14. Article
  15. Aging, cellular senescence and Parkinson's disease.Journal of Parkinson's disease · 2025
    Review
  16. Review
  17. Review
  18. Article
  19. Review
  20. Natural variation in age-related dopamine neuron degeneration is glutathione dependent and linked to life span.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article

13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Xi ChenCenter for Neurodegenerative Science, Van Andel Research Institute, Grand Rapids, MI 49503.
Jennifer K KordichCenter for Neurodegenerative Science, Van Andel Research Institute, Grand Rapids, MI 49503.
Erin T WilliamsCenter for Neurodegenerative Science, Van Andel Research Institute, Grand Rapids, MI 49503.
Nathan LevineCenter for Neurodegenerative Science, Van Andel Research Institute, Grand Rapids, MI 49503.
Allyson Cole-StraussDepartment of Translational Science and Molecular Medicine, Michigan State University, Grand Rapids, MI 49503.
Lee MarshallCenter for Neurodegenerative Science, Van Andel Research Institute, Grand Rapids, MI 49503.
Viviane LabrieCenter for Neurodegenerative Science, Van Andel Research Institute, Grand Rapids, MI 49503.
Jiyan MaCenter for Neurodegenerative Science, Van Andel Research Institute, Grand Rapids, MI 49503.ORCID 0000-0001-7150-1898
Jack W LiptonDepartment of Translational Science and Molecular Medicine, Michigan State University, Grand Rapids, MI 49503.
Darren J MooreCenter for Neurodegenerative Science, Van Andel Research Institute, Grand Rapids, MI 49503; Darren.Moore@vai.org.
Van Andel Institute · USMichigan State University · US

Funding

Mechanisms of VPS35-Dependent Neurodegeneration in Parkinson's DiseaseR01NS105432 · NINDS · VAN ANDEL RESEARCH INSTITUTE · PI MOORE, DARREN JOHN · 2017 to 2021
$2.1M
NINDS NIH HHS R01 NS105432
6 · The paper itself

Abstract

Mutations in the

Indexed as

alpha-SynucleinAnimalsDisease Models, AnimalDopaminergic NeuronsGene Knock-In TechniquesMaleMiceMutationNervous System DiseasesNeurodegenerative DiseasesNeuropathologyParkinson DiseaseProtein Transporttau ProteinsVesicular Transport Proteinsalpha-SynucleinMapt protein, mousetau ProteinsVesicular Transport ProteinsVps35 protein, mouseanimal modelneurodegenerationParkinson’s diseaseretromertau

Identifiers

PMID30842285
PMCPMC6431187
OpenAlexW2920510256

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.