Evidence map›Paper›PMID 30842249›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2019

Developmental Remodeling of Thalamic Interneurons Requires Retinal Signaling.

Naomi E Charalambakis, Gubbi Govindaiah, Peter W Campbell, William Guido

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 49 citations in OpenAlex.

  1. Thalamic Activity Regulates Interneuron Density in the Developing Visual Thalamus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
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  10. mGluR5 in hippocampal CA1 pyramidal neurons mediates stress-induced anxiety-like behavior.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2023
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  11. Article
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  16. Cre driver mouse lines for thalamocortical circuit mapping.The Journal of comparative neurology · 2022
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  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Naomi E CharalambakisDepartment of Anatomical Sciences and Neurobiology, University of Louisville School of Medicine, Louisville, Kentucky 40292.
Gubbi GovindaiahDepartment of Anatomical Sciences and Neurobiology, University of Louisville School of Medicine, Louisville, Kentucky 40292.
Peter W CampbellDepartment of Anatomical Sciences and Neurobiology, University of Louisville School of Medicine, Louisville, Kentucky 40292.
William GuidoDepartment of Anatomical Sciences and Neurobiology, University of Louisville School of Medicine, Louisville, Kentucky 40292 william.guido@louisville.edu.
University of Louisville · US

Funding

FUNCTIONAL STATE OF DEVELOPING RETINOGENICULATE SYNAPSER01EY012716 · NEI · VIRGINIA COMMONWEALTH UNIVERSITY · PI GUIDO, WILLIAM · 2001 to 2021
$6.9M
Formation and Maturation of Projections Between Thalamic Reticular Nucleus and Dorsal Lateral Geniculate NucleusF30EY026792 · NEI · UNIVERSITY OF LOUISVILLE · PI CAMPBELL, PETER W · 2017 to 2020
$161k
NEI NIH HHS F30 EY026792NEI NIH HHS R01 EY012716
6 · The paper itself

Abstract

The dorsal lateral geniculate nucleus (dLGN) of the mouse is a model system to study the development of thalamic circuitry. Most studies focus on relay neurons of dLGN, yet little is known about the development of the other principal cell type, intrinsic interneurons. Here we examined whether the structure and function of interneurons relies on retinal signaling. We took a loss-of-function approach and crossed GAD67-GFP mice, which express GFP in dLGN interneurons, with

Indexed as

Action PotentialsAnimalsBasic Helix-Loop-Helix ProteinsCell MovementFemaleGABAergic NeuronsGeniculate BodiesInterneuronsMaleMice, Inbred C57BLMice, KnockoutNerve Tissue ProteinsRetinal Ganglion CellsVisual PathwaysAtoh7 protein, mouseBasic Helix-Loop-Helix ProteinsNerve Tissue Proteinsdorsal lateral geniculate nucleusintrinsic interneuronsmouseretinogeniculatethalamus

Identifiers

PMID30842249
PMCPMC6520504
OpenAlexW2918451659

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.