Evidence map›Paper›PMID 30842235›Full record

ArticleJournal of clinical microbiology2019

Prognostic Indicators of Recurrence of Bacterial Vaginosis.

Jack D Sobel, Navkiranjot Kaur, Nicole A Woznicki, Dina Boikov, Tina Aguin, Gurveer Gill, Robert A Akins

Open access · bronzeAbstract read
In one paragraph

Article in Journal of clinical microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Article
  6. Article
  7. Article
  8. Article
  9. Vulvovaginitis in pregnant women.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2024
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Astodrimer sodium and bacterial vaginosis: a mini review.Archives of gynecology and obstetrics · 2022
    Review
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jack D SobelDivision of Infectious DiseasesWayne State University School of Medicine, Detroit, Michigan, USA jsobel@med.wayne.edu rakins@med.wayne.edu.
Navkiranjot KaurDepartment of Microbiology, Immunology, and Biochemistry, Wayne State University School of Medicine, Detroit, Michigan, USA.
Nicole A WoznickiDivision of Infectious DiseasesWayne State University School of Medicine, Detroit, Michigan, USA.
Dina BoikovDivision of Infectious DiseasesWayne State University School of Medicine, Detroit, Michigan, USA.
Tina AguinDepartment of Obstetrics and Gynecology, Wayne State University School of Medicine, Detroit, Michigan, USA.
Gurveer GillDepartment of Microbiology, Immunology, and Biochemistry, Wayne State University School of Medicine, Detroit, Michigan, USA.
Robert A AkinsDepartment of Microbiology, Immunology, and Biochemistry, Wayne State University School of Medicine, Detroit, Michigan, USA jsobel@med.wayne.edu rakins@med.wayne.edu.
Wayne State University · US

Funding

Validation of a novel diagnostic, prognostic assay for bacterial vaginosisR21AI111103 · NIAID · WAYNE STATE UNIVERSITY · PI AKINS, ROBERT A · 2014 to 2015
$405k
NIAID NIH HHS R21 AI111103
6 · The paper itself

Abstract

Following all forms of therapy for bacterial vaginosis (BV), recurrence rates are extremely high. Many diagnostic tests are available that differentiate bacterial vaginosis from other types of vaginal disorders, but none predict recurrence after treatment, nor are any vetted for monitoring ongoing responses to treatment. Our goal was to determine which tests, and at what optimal times, have prognostic value in predicting recurrence. This prospective cohort study monitored 74 highly recurrent BV patients for up to 9 months. Symptomatic BV patients were treated with oral metronidazole and were evaluated at cessation of treatment and monthly. Index tests included Amsel, Nugent, BV Blue, and Affirm VPIII, as well as a quantitative PCR (qPCR)-based test under initial evaluation here. The qPCR-based LbRC (

Indexed as

AdultAnti-Bacterial AgentsCross-Over StudiesDNA, BacterialFemaleHumansMetronidazoleMiddle AgedPredictive Value of TestsPrognosisProspective StudiesRecurrenceVaginaVaginosis, BacterialYoung AdultAnti-Bacterial AgentsDNA, BacterialMetronidazoleAffirm VPIIIAmsel criteriabacterial vaginosisBV BlueLactobacillusmetronidazoleNugent score

Identifiers

PMID30842235
PMCPMC6498020
OpenAlexW2921706353

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.