Evidence map›Paper›PMID 30842116›Full record

ArticleBMJ open2019

A priori choice of neuraxial labour analgesia and breastfeeding initiation success: a community-based cohort study in an Italian baby-friendly hospital.

Roberto Giorgio Wetzl, Enrica Delfino, Luca Peano, Daniela Gogna, Yvette Vidi, Francesca Vielmi, Eleonora Bianquin, Serena Cerioli, Maria Enrica Bettinelli, Maria Lorella Giannì and 3 more

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Roberto Giorgio WetzlDepartment of Anaesthesia, Intensive Care, and Out-hospital Emergency, Ospedale Regionale della Valle d'Aosta, Aosta, Valle d'Aosta, Italy.
Enrica DelfinoDepartment of Anaesthesia, Intensive Care, and Out-hospital Emergency, Ospedale Regionale della Valle d'Aosta, Aosta, Valle d'Aosta, Italy.
Luca PeanoMother-Child Department, Ospedale Regionale della Valle d'Aosta, Aosta, Valle d'Aosta, Italy.
Daniela GognaDepartment of Anaesthesia, Intensive Care, and Out-hospital Emergency, Ospedale Regionale della Valle d'Aosta, Aosta, Valle d'Aosta, Italy.
Yvette VidiDepartment of Anaesthesia, Intensive Care, and Out-hospital Emergency, Ospedale Regionale della Valle d'Aosta, Aosta, Valle d'Aosta, Italy.
Francesca VielmiMother-Child Department, Ospedale Regionale della Valle d'Aosta, Aosta, Valle d'Aosta, Italy.
Eleonora BianquinMother-Child Department, Ospedale Regionale della Valle d'Aosta, Aosta, Valle d'Aosta, Italy.
Serena CerioliDepartment of Anaesthesia, Intensive Care, and Out-hospital Emergency, Ospedale Regionale della Valle d'Aosta, Aosta, Valle d'Aosta, Italy.
Maria Enrica BettinelliMother and Child Health Unit, Agenzia di Tutela della Salute della Città Metropolitana di Milano, Milano, Italy.
Maria Lorella GiannìDepartment of Clinical Sciences and Community Health, Fondazione IRCCS Cà Granda, Study University of Milan, Milano, Italy.
Gabriella FrassyDepartment of Anaesthesia, Intensive Care, and Out-hospital Emergency, Ospedale Regionale della Valle d'Aosta, Aosta, Valle d'Aosta, Italy.
Elena BorisDepartment of Anaesthesia, Intensive Care, and Out-hospital Emergency, Ospedale Regionale della Valle d'Aosta, Aosta, Valle d'Aosta, Italy.
Cesare ArioniMother-Child Department, Ospedale Regionale della Valle d'Aosta, Aosta, Valle d'Aosta, Italy.
Azienda USL della Valle d’Aosta · ITFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITMetropolitana Milanese (Italy) · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate whether the nature of the decision about receiving neuraxial labour analgesia is associated with breastfeeding initiation success (BIS), defined as exclusive breastfeeding until discharge associated with postnatal weight loss <7% at 60 hours from birth.

designSingle-centre community-based cohort study.

settingAn Italian baby-friendly hospital, from 1 July 2011 to 22 September 2015.

participantsInclusion criteria: women vaginally delivering singleton cephalic newborns and willing to breastfeed. EXCLUSION CRITERIA: women who delivered in uterus-dead fetuses, were single or requested but did not receive neuraxial analgesia. Overall, 775 out of the 3628 enrolled women received neuraxial analgesia.

resultsCompared with women who tried to cope with labour pain, those who decided a priori to receive neuraxial analgesia had less BIS (planned vaginal birth: 2121/3421 (62.0%), vs 102/207 (49.3%; p<0.001; risk difference (RD), 12.7%); actual vaginal birth: 1924/2994 (64.3%), vs 93/189 (49.2%; p<0.001; RD, 15.1%)). Multivariable analyses with antelabour-only confounders confirmed both associations (planned vaginal birth: relative risk (RR), 0.65; 95% CI, 0.48 to 0.87; actual vaginal birth: RR, 0.59; 95% CI, 0.43 to 0.80). Although women who requested analgesia as a last resort had less BIS than did those successfully coping with labour pain in the bivariable analyses (planned vaginal birth: 1804/2853 (63.2%), vs 317/568 (55.8%; p=0.001; RD, 7.4%); actual vaginal birth: 1665/2546 (65.4%), vs 259/448 (57.8%; p=0.002; RD, 7.6%)), multivariable analyses with either antelabour-only or peripartum confounders did not confirm these associations (planned vaginal birth: RR, 0.99; 95% CI, 0.80 to 1.23; actual vaginal birth: RR, 0.90; 95% CI, 0.69 to 1.16).

conclusionsCompared with trying to cope with labour pain, a priori choice of neuraxial analgesia is negatively associated with BIS. Conversely, compared with having successfully coped with pain, requesting neuraxial analgesia as a last resort is not negatively associated with BIS.

Indexed as

AdultAnalgesia, ObstetricalBreast FeedingCesarean SectionCohort StudiesFemaleHumansInfant, NewbornItalyLabor PainPregnancyPrenatal Careanaesthesia in obstetricsperinatologytoxicology

Identifiers

PMID30842116
PMCPMC6429869
OpenAlexW2921759710

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.