ArticleBMC medicine2019
What causes severe malaria and its complications in children? Lessons learned over the past 15 years.
Article in BMC medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- A Pilot Feasibility Study of a Home Tablet-Based Neurorehabilitation Program and Serial Brain Vital Sign Monitoring for Survivors of Pediatric Cerebral Malaria.The American journal of tropical medicine and hygiene · 2026Article
- Clinical spectrum and management outcomes of acute febrile illness Among children attending health facilities in northwestern Tanzania, 2020-2021.Frontiers in pediatrics · 2026Article
- Prevalence and distribution of Plasmodium falciparum multidrug resistant 1 D1246Y allele among children in Ibadan Southwest, Nigeria.Scientific reports · 2025Article
- Clinical and Laboratory Predictors of Poor Outcomes in Pediatric Cerebral Malaria in Nigeria.Oman medical journal · 2024Article
- Apolipoprotein-E4: risk of severe malaria and mortality and cognitive impairment in pediatric cerebral malaria.Pediatric research · 2024Article
- A human pluripotent stem cell-derived in vitro model of the blood-brain barrier in cerebral malaria.Fluids and barriers of the CNS · 2024Article
- Exploring the hidden mental health consequences of malaria beyond the fever.Frontiers in human neuroscience · 2024Review
- Host-Derived Extracellular Vesicles in Blood and Tissue Human Protozoan Infections.Microorganisms · 2023Review
- Novel Therapeutics for Malaria.Pharmaceutics · 2023Review
- Article
- Blood biomarkers of neuronal injury in paediatric cerebral malaria and severe malarial anaemia.Brain communications · 2023Article
- Evaluating the impact of COVID-19 pandemic on complicated malaria admissions and outcomes in the paediatric Ho Teaching Hospital of the Volta Region of Ghana.PLOS global public health · 2022Article
- Malaria Related Neurocognitive Deficits and Behavioral Alterations.Frontiers in cellular and infection microbiology · 2022Review
- Factors Associated with Uptake of Intermittent Preventive Treatment for Malaria During Pregnancy. Analysis of Data from the Tanzania 2015-2016 Demographic Health Survey and Malaria Indicator Survey.The East African health research journal · 2022Article
- Association of Plasma Tau With Mortality and Long-term Neurocognitive Impairment in Survivors of Pediatric Cerebral Malaria and Severe Malarial Anemia.JAMA network open · 2021Article
- Article
- Spontaneous Splenic Rupture as a Complication of Malaria and Incidental Acute Appendicitis: A Case Report.Cureus · 2021Article
- Fine scale analysis of malaria incidence in under-5: hierarchical Bayesian spatio-temporal modelling of routinely collected malaria data between 2012-2018 in Cameroon.Scientific reports · 2021Article
- Chloroquine and Sulfadoxine-Pyrimethamine Resistance in Sub-Saharan Africa-A Review.Frontiers in genetics · 2021Review
- 17β-Estradiol Is Involved in the Sexual Dimorphism of the Immune Response to Malaria.Frontiers in endocrinology · 2021Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Over the past 15 years, malaria mortality has reduced by approximately 50%. However, malaria still causes more than 400,000 deaths annually, most of which occur in African children under 5 years of age. Significant advances in understanding the pathogenesis of the disease provide a basis for future work to prevent severe malaria and its complications. Herein, we provide an overview of advances in our understanding of severe malaria in African children over the past 15 years, highlighting key complications and identifying priorities to further reduce malaria-associated mortality.
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