Evidence map›Paper›PMID 30841634›Full record

ArticleCells2019

Licochalcone A Inhibits Cellular Motility by Suppressing E-cadherin and MAPK Signaling in Breast Cancer.

Wen-Chung Huang, Haiso-Han Su, Li-Wen Fang, Shu-Ju Wu, Chian-Jiun Liou

Open access · goldAbstract read
In one paragraph

Article in Cells, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. A Novel Tri-Hydroxy-Methylated Chalcone Isolated fromInternational journal of molecular sciences · 2023
    Article
  10. Article
  11. Anticancer Potential of Natural Chalcones: In Vitro and In Vivo Evidence.International journal of molecular sciences · 2023
    Review
  12. Review
  13. [Licochalcone A induces cell cycle arrest in human lung squamous carcinoma cellsNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2023
    Article
  14. Article
  15. Licorice (OncoTargets and therapy · 2022
    Review
  16. Pharmacological Effects and Underlying Mechanisms of Licorice-Derived Flavonoids.Evidence-based complementary and alternative medicine : eCAM · 2022
    Review
  17. Article
  18. Review
  19. Article
  20. Anticancer Activity of Natural and Synthetic Chalcones.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Wen-Chung HuangGraduate Institute of Health Industry Technology, Research Center for Food and Cosmetic Safety, College of Human Ecology, Chang Gung University of Science and Technology, Taoyuan City 33303, Taiwan. wchuang@mail.cgust.edu.tw.
Haiso-Han SuGraduate Institute of Health Industry Technology, Research Center for Food and Cosmetic Safety, College of Human Ecology, Chang Gung University of Science and Technology, Taoyuan City 33303, Taiwan. candy08117@gmail.com.
Li-Wen FangDepartment of Nutrition, I-Shou University, Kaohsiung 82445, Taiwan. fanglw@isu.edu.tw.
Shu-Ju WuDepartment of Nutrition and Health Sciences, Research Center for Chinese Herbal Medicine, College of Human Ecology, Chang Gung University of Science and Technology, Taoyuan City 33303, Taiwan. sjwu@mail.cgust.edu.tw.
Chian-Jiun LiouDivision of Allergy, Asthma, and Rheumatology, Department of Pediatrics, Chang Gung Memorial Hospital, Linkou, Taoyuan City 33303, Taiwan. ccliu@mail.cgust.edu.tw.
Chang Gung University of Science and Technology · TWChang Gung Memorial Hospital · TWI-Shou University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A compound isolated from

Indexed as

MAP Kinase Signaling SystemApoptosisAutophagyBreast NeoplasmsCadherinsCell CycleCell Line, TumorCell MovementCell ProliferationCell SurvivalChalconesDNA DamageFemaleHumansMembrane Potential, MitochondrialModels, BiologicalCadherinsChalconeslicochalcone APeroxisome Proliferator-Activated ReceptorsProto-Oncogene Proteins c-aktReactive Oxygen Speciesapoptosiscaspase-3cellular motilitylicochalcone AMDA-MB-231 cells

Identifiers

PMID30841634
PMCPMC6468539
OpenAlexW2919971531

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.