Evidence map›Paper›PMID 30841576›Full record

ArticleMolecules (Basel, Switzerland)2019

Surface Structuring Combined with Chemical Surface Functionalization: An Effective Tool to Manipulate Cell Adhesion.

Sarah M Elsayed, Stefan Paschke, Sibylle J Rau, Karen Lienkamp

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sarah M ElsayedFreiburg Center for Interactive Materials and Bioinspired Technologies (FIT) and Department of Microsystems Engineering (IMTEK), Albert-Ludwigs-Universität, Georges-Köhler-Allee 105, 79110 Freiburg, Germany. sarah.mahmoud@imtek.uni-freiburg.de.
Stefan PaschkeFreiburg Center for Interactive Materials and Bioinspired Technologies (FIT) and Department of Microsystems Engineering (IMTEK), Albert-Ludwigs-Universität, Georges-Köhler-Allee 105, 79110 Freiburg, Germany. stefan.paschke@imtek.uni-freiburg.de.
Sibylle J RauFreiburg Center for Interactive Materials and Bioinspired Technologies (FIT) and Department of Microsystems Engineering (IMTEK), Albert-Ludwigs-Universität, Georges-Köhler-Allee 105, 79110 Freiburg, Germany. sibylle.rau@uniklinik-freiburg.de.
Karen LienkampFreiburg Center for Interactive Materials and Bioinspired Technologies (FIT) and Department of Microsystems Engineering (IMTEK), Albert-Ludwigs-Universität, Georges-Köhler-Allee 105, 79110 Freiburg, Germany. lienkamp@imtek.uni-freiburg.de.ORCID 0000-0001-6868-3707

Funding

Egyptian Ministry of Higher Education (Egyptian Missions) PhD Grant for S.M.E.Ministerium für Wissenschaft, Forschung und Kunst Baden-Württemberg GenMik Graduate School
6 · The paper itself

Abstract

In this study, we investigate how a surface structure underneath a surface-attached polymer coating affects the bioactivity of the resulting material. To that end, structured surfaces were fabricated using colloidal lithography (lateral dimensions: 200 nm to 1 µm, height ~15 to 50 nm). The surface structures were further functionalized either with antimicrobial, cell-adhesive polycations or with protein-repellent polyzwitterions. The materials thus obtained were compared to non-functionalized structured surfaces and unstructured polymer monolayers. Their physical properties were studied by contact-angle measurements and atomic force microscopy (AFM). Protein adhesion was studied by surface plasmon resonance spectroscopy, and the antimicrobial activity against

Indexed as

Surface PropertiesAnti-Infective AgentsBacterial AdhesionBiocompatible MaterialsCell SurvivalKeratinocytesMicroscopy, Atomic ForcePolymersProteinsSurface Plasmon ResonanceAnti-Infective AgentsBiocompatible MaterialsPolymersProteinscolloidal lithographypolymer surfacessurface-cell interactionssurface functionalizationsurface structuringtissue engineering

Identifiers

PMID30841576
PMCPMC6429452

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.