ArticleNanomaterials (Basel, Switzerland)2019
Cell Imaging Using Two-Photon Excited CdS Fluorescent Quantum Dots Working within the Biological Window.
Article in Nanomaterials (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Interfacial engineering with chemical bath deposition for high-performance HgTe quantum dot-based short-wave infrared photodetectors.Nano convergence · 2025Article
- Sustainable Scalable Mechanochemical Synthesis of CdS/BiNanomaterials (Basel, Switzerland) · 2024Article
- Impedance Spectroscopy Analysis of PbSe Nanostructures Deposited by Aerosol Assisted Chemical Vapor Deposition Approach.Nanomaterials (Basel, Switzerland) · 2021Article
- Photoluminescence of InAs/GaAs quantum dots under direct two-photon excitation.Scientific reports · 2020Article
- Nanomedicines for Near-Infrared Fluorescent Lifetime-Based Bioimaging.Frontiers in bioengineering and biotechnology · 2019Review
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
In recent years, two-photon excited semiconductor quantum dots (QDs) have been the subject of intense investigation due to their long excitation wavelength which helps to achieve deeper penetration and higher image resolution in optical bioimaging. In this paper, water-soluble CdS QDs were synthesized using a hydrothermal method and applied to human liver hepatocellular carcinoma (HepG2) cells. The first-principles calculation suggested that the S-rich defected structure contributes to a narrower band gap compared to the pristine structure. The resulting fluorescence wavelength was significantly red shifted, which was attributed to the deep defect states emission. The large Stokes shifts (> 200 nm) of the QDs can eliminate the possible cross-talk between the excitation light and the emission light. Two-photon induced red fluorescence emission can avoid overlapping with the autofluorescence emission of biological samples. The uptake and cell viability measurements of the HepG2 cells showed a good biocompatibility and a low toxicity of CdS QDs. Two-photon excited scanning microscopy images revealed that the HepG2 cells incubated with CdS QDs emitted bright red upconversion fluorescence and the fluorescence brightness was 38.2 times of that of the control group. These results support CdS QDs as a good candidate for application in cellular imaging.
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Registered trials
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