Evidence map›Paper›PMID 30841529›Full record

ArticleInternational journal of molecular sciences2019

Regulatory Effect of DNA Topoisomerase I on T3SS Activity, Antibiotic Susceptibility and Quorum- Sensing-Independent Pyocyanin Synthesis in

Rong Yan, Shikun Hu, Ning Ma, Peiqing Song, Qingqing Liang, Huiqun Zhang, Yanqi Li, Lixin Shen, Kangmin Duan, Lin Chen

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.7field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Phage-host interaction inApplied and environmental microbiology · 2025
    Article
  3. Small Molecule Inhibitors ofInternational journal of molecular sciences · 2024
    Article
  4. AApplied and environmental microbiology · 2024
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Rong YanKey Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, Xi'an 710069, Shaanxi, China. yanrongswallow@gmail.com.
Shikun HuKey Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, Xi'an 710069, Shaanxi, China. hushikun@stumail.nwu.edu.cn.
Ning MaKey Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, Xi'an 710069, Shaanxi, China. maning@stumail.nwu.edu.cn.
Peiqing SongKey Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, Xi'an 710069, Shaanxi, China. 201631710@stumail.nwu.edu.cn.
Qingqing LiangKey Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, Xi'an 710069, Shaanxi, China. qingqingl@stumail.nwu.edu.cn.
Huiqun ZhangKey Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, Xi'an 710069, Shaanxi, China. baihezhaohui@stumail.nwu.edu.cn.
Yanqi LiDepartment of Oral Biology, Rady Faculty of Health Sciences, University of Manitoba, 780 Bannatyne Ave., Winnipeg, MB R3E 0W2, Canada. liy34544@myumanitoba.ca.
Lixin ShenKey Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, Xi'an 710069, Shaanxi, China. shenlx@nwu.edu.cn.
Kangmin DuanKey Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, Xi'an 710069, Shaanxi, China. Kangmin.Duan@umanitoba.ca.ORCID 0000-0002-3016-786X
Lin ChenKey Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, Xi'an 710069, Shaanxi, China. chenlin@nwu.edu.cn.ORCID 0000-0002-3016-786X
Ministry of Education of the People's Republic of China · CNUniversity of Manitoba · CA

Funding

Changjiang Scholar Program of Chinese Ministry of Education IRT-15R55Natural Science Foundation of Shaanxi Provincial Department of Education 2018JM3013Natural Sciences and Engineering Research Council of Canada 31570131Natural Sciences and Engineering Research Council of Canada 402943-2011 RGPIN
6 · The paper itself

Abstract

Topoisomerases are required for alleviating supercoiling of DNA during transcription and replication. Recent evidence suggests that supercoiling of bacterial DNA can affect bacterial pathogenicity. To understand the potential regulatory role of a topoisomerase I (TopA) in

Indexed as

Drug Resistance, BacterialBacterial ProteinsDNA Topoisomerases, Type IPseudomonas aeruginosaPyocyanineQuorum SensingType III Secretion SystemsBacterial ProteinsDNA Topoisomerases, Type IPyocyanineType III Secretion Systemsantibiotic susceptibilitybiofilmDNA TopoisomeraseprtNPseudomonas aeruginosaPyocyanintype III secretion system

Identifiers

PMID30841529
PMCPMC6429228
OpenAlexW2918792618

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.