Evidence map›Paper›PMID 30841519›Full record

ArticleInternational journal of molecular sciences2019

Bioproduction of Quercetin and Rutinose Catalyzed by Rutinosidase: Novel Concept of "Solid State Biocatalysis".

Jana Kapešová, Lucie Petrásková, Kristína Markošová, Martin Rebroš, Michael Kotik, Pavla Bojarová, Vladimír Křen

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Multidimensional mechanisms of quercetin in diabetic kidney disease.Frontiers in cell and developmental biology · 2025
    Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Dual Substrate Specificity of the Rutinosidase fromInternational journal of molecular sciences · 2020
    Article
  16. Biocatalysis: "A Jack of all Trades..."International journal of molecular sciences · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 3 countries.

Jana KapešováInstitute of Microbiology of the Czech Academy of Sciences, Laboratory of Biotransformation, Vídeňská 1083, CZ 14220 Prague 4, Czech Republic. janakapesova@gmail.com.
Lucie PetráskováInstitute of Microbiology of the Czech Academy of Sciences, Laboratory of Biotransformation, Vídeňská 1083, CZ 14220 Prague 4, Czech Republic. petraskova@biomed.cas.cz.
Kristína MarkošováInstitute of Biotechnology, Slovak University of Technology, Radlinského 9, 81237 Bratislava, Slovakia. kristina.markosova@stuba.sk.
Martin RebrošInstitute of Biotechnology, Slovak University of Technology, Radlinského 9, 81237 Bratislava, Slovakia. martin.rebros@stuba.sk.
Michael KotikInstitute of Microbiology of the Czech Academy of Sciences, Laboratory of Biotransformation, Vídeňská 1083, CZ 14220 Prague 4, Czech Republic. kotik@biomed.cas.cz.
Pavla BojarováInstitute of Microbiology of the Czech Academy of Sciences, Laboratory of Biotransformation, Vídeňská 1083, CZ 14220 Prague 4, Czech Republic. bojarova@biomed.cas.cz.
Vladimír KřenInstitute of Microbiology of the Czech Academy of Sciences, Laboratory of Biotransformation, Vídeňská 1083, CZ 14220 Prague 4, Czech Republic. kren@biomed.cas.cz.ORCID 0000-0002-1091-4020
Czech Academy of Sciences · CZSlovak University of Technology in Bratislava · SK

Funding

Grantová Agentura České Republiky 18-00150SSlovak Research Agency ITMS 26230120006
6 · The paper itself

Abstract

Quercetin is a flavonoid largely employed as a phytochemical remedy and a food or dietary supplement. We present here a novel biocatalytic methodology for the preparation of quercetin from plant-derived rutin, with both substrate and product being in mostly an undissolved state during biotransformation. This "solid-state" enzymatic conversion uses a crude enzyme preparation of recombinant rutinosidase from

Indexed as

BiocatalysisAspergillus nigerDisaccharidesFungal ProteinsGlycoside HydrolasesIndustrial MicrobiologyPichiaQuercetinRutinbeta-rutinosidaseDisaccharidesFungal ProteinsGlycoside HydrolasesQuercetinRutinrutinoseAspergillus nigerquercetinrutinrutinoserutinosidase“solid-state biocatalysis”

Identifiers

PMID30841519
PMCPMC6429052
OpenAlexW2919413130

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.