Evidence map›Paper›PMID 30841499›Full record

ArticleInternational journal of molecular sciences2019

HDAC Inhibitors Induce

Amir Bagheri, Parham Habibzadeh, Seyedeh Fatemeh Razavipour, Claude-Henry Volmar, Nancy T Chee, Shaun P Brothers, Claes Wahlestedt, Seyed Javad Mowla, Mohammad Ali Faghihi

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Epigenetic manipulation of anterior insular cortex alters neural signals and cognitive control.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2025
    Article
  5. Intepirdine Derivatives Possessing Dual 5HT6 Antagonism / HDAC6 Inhibitory Activity.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025
    Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. D1R-5-HT2AR Uncoupling Reduces Depressive Behaviours via HDAC Signalling.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2023
    Article
  11. Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Amir BagheriDepartment of Molecular Genetics, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, P.O. Box 14115-111, Iran. axb1907@med.miami.edu.
Parham HabibzadehPersian BayanGene Research and Training Center, Shiraz, P.O. Box 7134767617, Iran. Parham.Habibzadeh@yahoo.com.ORCID 0000-0002-2086-0425
Seyedeh Fatemeh RazavipourDepartment of Biochemistry and Molecular Biology, University of Miami Miller School of Medicine, Miami, FL 33136, USA. sxr986@med.miami.edu.
Claude-Henry VolmarCenter for Therapeutic Innovation and Department of Psychiatry & Behavioral Sciences, University of Miami Miller School of Medicine, Miami, FL 33136, USA. cvolmar@miami.edu.ORCID 0000-0001-9437-051X
Nancy T CheeCenter for Therapeutic Innovation and Department of Psychiatry & Behavioral Sciences, University of Miami Miller School of Medicine, Miami, FL 33136, USA. ntm30@med.miami.edu.
Shaun P BrothersCenter for Therapeutic Innovation and Department of Psychiatry & Behavioral Sciences, University of Miami Miller School of Medicine, Miami, FL 33136, USA. sbrothers@umail.miami.edu.
Claes WahlestedtCenter for Therapeutic Innovation and Department of Psychiatry & Behavioral Sciences, University of Miami Miller School of Medicine, Miami, FL 33136, USA. CWahlestedt@med.miami.edu.
Seyed Javad MowlaDepartment of Molecular Genetics, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, P.O. Box 14115-111, Iran. sjmowla@modares.ac.ir.
Mohammad Ali FaghihiCenter for Therapeutic Innovation and Department of Psychiatry & Behavioral Sciences, University of Miami Miller School of Medicine, Miami, FL 33136, USA. mfaghihi@med.miami.edu.

Funding

Epigenetic Signaling Pathways Contributing to Alcohol DependenceR01AA023781 · NIAAA · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI HEILIG, MARKUS ALEXANDER, WAHLESTEDT, CLAES ROBERT · 2015 to 2019
$2.1M
NIH HHS NIH NINDS R01NS081208-01A1NIMAD research grant 940714
6 · The paper itself

Abstract

Besides its key role in neural development, brain-derived neurotrophic factor (BDNF) is important for long-term potentiation and neurogenesis, which makes it a critical factor in learning and memory. Due to the important role of BDNF in synaptic function and plasticity, an in-house epigenetic library was screened against human neural progenitor cells (HNPCs) and WS1 human skin fibroblast cells using Cell-to-Ct assay kit to identify the small compounds capable of modulating the

Indexed as

Neuronal OutgrowthBenzimidazolesBenzofuransBrain-Derived Neurotrophic FactorCells, CulturedHEK293 CellsHistone Deacetylase InhibitorsHumansHydroxamic AcidsNeural Stem CellsabexinostatBenzimidazolesBenzofuransBrain-Derived Neurotrophic FactorHistone Deacetylase InhibitorsHydroxamic AcidsquisinostatSB939 compoundBDNFepigenetic libraryHDAC inhibitorhuman neural progenitor cellneurite outgrowthneurodegenerative disorderscreening

Identifiers

PMID30841499
PMCPMC6429164

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.