Evidence map›Paper›PMID 30841497›Full record

ReviewViruses2019

Ecological and Evolutionary Processes Shaping Viral Genetic Diversity.

Cas Retel, Hanna Märkle, Lutz Becks, Philine G D Feulner

Abstract readReview
In one paragraph

Review in Viruses, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Review
  2. Genomic analysis ofVirus evolution · 2026
    Article
  3. RNA Large Language Models in Virology.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Measuring genetic diversity across populations.PLoS computational biology · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Modeling the Climatic Suitability of COVID-19 Cases in Brazil.Tropical medicine and infectious disease · 2023
    Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Cas RetelDepartment of Fish Ecology and Evolution, Center for Ecology, Evolution and Biogeochemistry, EAWAG, Swiss Federal Institute of Aquatic Science and Technology, 6047 Kastanienbaum, Switzerland. cas.retel@eawag.ch.
Hanna MärkleSection of Population Genetics, TUM School of Life Sciences Weihenstephan, Technical University of Munich, 85354 Freising, Germany. hanna.maerkle@tum.de.
Lutz BecksLimnological Institute University Konstanz, Aquatic Ecology and Evolution, 78464 Konstanz, Germany. lutz.becks@uni-konstanz.de.ORCID 0000-0002-3885-5253
Philine G D FeulnerDepartment of Fish Ecology and Evolution, Center for Ecology, Evolution and Biogeochemistry, EAWAG, Swiss Federal Institute of Aquatic Science and Technology, 6047 Kastanienbaum, Switzerland. philine.feulner@eawag.ch.ORCID 0000-0002-8078-1788

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The contemporary genomic diversity of viruses is a result of the continuous and dynamic interaction of past ecological and evolutionary processes. Thus, genome sequences of viruses can be a valuable source of information about these processes. In this review, we first describe the relevant processes shaping viral genomic variation, with a focus on the role of host⁻virus coevolution and its potential to give rise to eco-evolutionary feedback loops. We further give a brief overview of available methodology designed to extract information about these processes from genomic data. Short generation times and small genomes make viruses ideal model systems to study the joint effect of complex coevolutionary and eco-evolutionary interactions on genetic evolution. This complexity, together with the diverse array of lifetime and reproductive strategies in viruses ask for extensions of existing inference methods, for example by integrating multiple information sources. Such integration can broaden the applicability of genetic inference methods and thus further improve our understanding of the role viruses play in biological communities.

Indexed as

EcosystemEvolution, MolecularGenetic VariationGenomicsHost Microbial InteractionsModels, BiologicalViruseseco-evolutionary feedbackgenetic diversityhost–virus coevolutionviral population genetics

Identifiers

PMID30841497
PMCPMC6466605

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.